Sofie Jacobs

Global Public Health R&D
Beerse, VLG, Belgium

Last Updated: 09/26/2026

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Found 20 publications

Optimal preclinical models for human dose projection of SARS-CoV-2 small molecule direct-acting antivirals.

Optimal preclinical models for human dose projection of SARS-CoV-2 small molecule direct-acting antivirals.

Journal: Antiviral research
Published: September 03, 2025

A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein.

A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein.

Journal: Nature
Published: February 21, 2024

Perturbation of Alphavirus and Flavivirus Infectivity by Components of the Bacterial Cell Wall.

Perturbation of Alphavirus and Flavivirus Infectivity by Components of the Bacterial Cell Wall.

Journal: Journal of virology
Published: February 02, 2022

An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.

An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.

Journal: Science translational medicine
Published: October 05, 2021

Posaconazole inhibits multiple steps of the alphavirus replication cycle.

Posaconazole inhibits multiple steps of the alphavirus replication cycle.

Journal: Antiviral research
Published: September 02, 2021

Corrigendum to "itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens".

Corrigendum to "itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens".

Journal: EBioMedicine
Published: June 29, 2021

The impact of obstructive sleep apnea on endothelial function during weight loss in an obese pediatric population.

The impact of obstructive sleep apnea on endothelial function during weight loss in an obese pediatric population.

Journal: Sleep medicine
Published: March 15, 2021

Favipiravir Does Not Inhibit Chikungunya Virus Replication in Mosquito Cells and Aedes aegypti Mosquitoes.

Favipiravir Does Not Inhibit Chikungunya Virus Replication in Mosquito Cells and Aedes aegypti Mosquitoes.

Journal: Microorganisms
Published: February 28, 2021

Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial.

Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial.

Journal: EBioMedicine
Published: November 25, 2020

Fatal encephalopathy with brainstem involvement under dabrafenib and trametinib in a BRAF-positive metastatic melanoma.

Fatal encephalopathy with brainstem involvement under dabrafenib and trametinib in a BRAF-positive metastatic melanoma.

Journal: Revue neurologique
Published: November 05, 2020

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: October 10, 2020

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters.

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters.

Journal: Nature communications
Published: September 18, 2020
Showing 1-12 of 20

Last Updated: 09/26/2026