Last Updated: 09/26/2026
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Found 13 publications
Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads.
Journal: Molecular pharmacology
Published: April 26, 2022
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 16, 2016
Synthesis and antifungal evaluation of head-to-head and head-to-tail bisamidine compounds.
Journal: Bioorganic & medicinal chemistry
Published: April 29, 2015
Diels-Alder reactions of five-membered heterocycles containing one heteroatom.
Journal: Tetrahedron letters
Published: April 04, 2015
Recent advances toward a molecular mechanism of efflux pump inhibition.
Journal: Frontiers in microbiology
Published: March 02, 2015
How do antimalarial drugs reach their intracellular targets?
Journal: Frontiers in pharmacology
Published: January 29, 2015
Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.
Journal: Bioorganic & medicinal chemistry
Published: January 09, 2015
Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitors.
Journal: Antimicrobial agents and chemotherapy
Published: August 13, 2014
Synthesis and antibacterial evaluation of new, unsymmetrical triaryl bisamidine compounds.
Journal: Bioorganic & medicinal chemistry letters
Published: April 14, 2014
Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coli.
Journal: Antimicrobial agents and chemotherapy
Published: November 20, 2013
Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: synthesis and SAR of novel analogs of MBX 1066 and MBX 1090.
Journal: Bioorganic & medicinal chemistry
Published: August 27, 2013
Solute restriction reveals an essential role for clag3-associated channels in malaria parasite nutrient acquisition.
Journal: Molecular pharmacology
Published: September 06, 2012
Last Updated: 09/26/2026