Soon Y. Shin

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 108 publications

6-(2-Hydroxybenzoyl)pyrazolo[1,5-a]pyrimidine-3‑carbonitriles as novel reactive oxygen species-generating anticancer agents inducing ER stress and DNA damage in EGFR-mutant non-small cell lung cancer.

6-(2-Hydroxybenzoyl)pyrazolo[1,5-a]pyrimidine-3‑carbonitriles as novel reactive oxygen species-generating anticancer agents inducing ER stress and DNA damage in EGFR-mutant non-small cell lung cancer.

Journal: Bioorganic & medicinal chemistry letters

Published: June 26, 2026

6-(5-bromo-2-hydroxybenzoyl)-2-((3-methoxyphenyl)amino)pyrazolo[1,5-a]pyrimidine-3‑carbonitrile promotes apoptosis by blocking the ERK MAP K-MCL1 signaling pathway in H1975 non-small cell lung cancer cells.

6-(5-bromo-2-hydroxybenzoyl)-2-((3-methoxyphenyl)amino)pyrazolo[1,5-a]pyrimidine-3‑carbonitrile promotes apoptosis by blocking the ERK MAP K-MCL1 signaling pathway in H1975 non-small cell lung cancer cells.

Journal: Bioorganic & medicinal chemistry letters

Published: May 13, 2026

Ageratum houstonianum Extract and Agerarin Promote Hair Growth via MAPK/AP-1 Axis-Dependent Upregulation of SCUBE3 in Human Dermal Papilla Cells.

Ageratum houstonianum Extract and Agerarin Promote Hair Growth via MAPK/AP-1 Axis-Dependent Upregulation of SCUBE3 in Human Dermal Papilla Cells.

Journal: International journal of molecular sciences

Published: March 06, 2026

EGR1 regulates IGF-1-stimulated pancreatic cancer cell invasion by increasing IL-11 expression.

EGR1 regulates IGF-1-stimulated pancreatic cancer cell invasion by increasing IL-11 expression.

Journal: Oncology letters

Published: March 03, 2026

Design, synthesis, and biological evaluation of naphthoaurones against colon cancer cells.

Design, synthesis, and biological evaluation of naphthoaurones against colon cancer cells.

Journal: Bioorganic & medicinal chemistry letters

Published: February 23, 2025

TLR2-EGR1 signaling axis modulates TGFβ1-induced differentiation of fibroblasts into myofibroblasts in pulmonary fibrosis.

TLR2-EGR1 signaling axis modulates TGFβ1-induced differentiation of fibroblasts into myofibroblasts in pulmonary fibrosis.

Journal: Biochemical and biophysical research communications

Published: October 07, 2024

Pyrazolo-1-carbothioamides as EGR-1-DNA binding disruptors.

Pyrazolo-1-carbothioamides as EGR-1-DNA binding disruptors.

Journal: Bioorganic & medicinal chemistry letters

Published: September 27, 2024

Therapeutic potential of a systemically applied humanized monoclonal antibody targeting Toll‑like receptor 2 in atopic‑dermatitis‑like skin lesions in a mouse model.

Therapeutic potential of a systemically applied humanized monoclonal antibody targeting Toll‑like receptor 2 in atopic‑dermatitis‑like skin lesions in a mouse model.

Journal: Biomedical reports

Published: September 22, 2024

(E)-3-(3-([1,1'-Biphenyl]-4-yl)-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-ones inducing reactive oxygen species generation through glutathione depletion.

(E)-3-(3-([1,1'-Biphenyl]-4-yl)-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-ones inducing reactive oxygen species generation through glutathione depletion.

Journal: Bioorganic & medicinal chemistry letters

Published: September 05, 2024

EGR1 interacts with p-SMAD at the endothelin-1 gene promoter to regulate gene expression in TGFβ1-stimulated IMR-90 fibroblasts.

EGR1 interacts with p-SMAD at the endothelin-1 gene promoter to regulate gene expression in TGFβ1-stimulated IMR-90 fibroblasts.

Journal: Biochemical and biophysical research communications

Published: August 06, 2024

L-Cysteine mitigates ROS-induced apoptosis and neurocognitive deficits by protecting against endoplasmic reticulum stress and mitochondrial dysfunction in mouse neuronal cells.

L-Cysteine mitigates ROS-induced apoptosis and neurocognitive deficits by protecting against endoplasmic reticulum stress and mitochondrial dysfunction in mouse neuronal cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: August 01, 2024

Saikosaponin A Recovers Impaired Filaggrin Levels in Inflamed Skin by Downregulating the Expression of FRA1 and c-Jun.

Saikosaponin A Recovers Impaired Filaggrin Levels in Inflamed Skin by Downregulating the Expression of FRA1 and c-Jun.

Journal: Molecules (Basel, Switzerland)

Published: July 12, 2024

Showing 1-12 of 108

Last Updated: 09/26/2026