Sophia Ladraa

149 Rue De Sèvres
Paris, 75015, France

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 13 publications

Oncogenic PIK3CA mutations shape an immunoregulatory microenvironment in mosaic overgrowth disorders.

Oncogenic PIK3CA mutations shape an immunoregulatory microenvironment in mosaic overgrowth disorders.

Journal: PNAS nexus

Published: January 23, 2026

PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect.

PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 24, 2025

Telomere occupancy by TRF2 is altered by KIT mutations and correlates with mastocytosis regression.

Telomere occupancy by TRF2 is altered by KIT mutations and correlates with mastocytosis regression.

Journal: Blood cancer journal

Published: May 24, 2025

Image pre-processing impact on generative model performance for Unsupervised Venous Malformation Segmentation.

Image pre-processing impact on generative model performance for Unsupervised Venous Malformation Segmentation.

Journal: Computer methods and programs in biomedicine

Published: March 23, 2025

Sotorasib for Vascular Malformations Associated with KRAS G12C Mutation.

Sotorasib for Vascular Malformations Associated with KRAS G12C Mutation.

Journal: The New England journal of medicine

Published: July 17, 2024

Targeted therapy for capillary-venous malformations.

Targeted therapy for capillary-venous malformations.

Journal: Signal transduction and targeted therapy

Published: October 02, 2023

Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibition.

Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibition.

Journal: The Journal of experimental medicine

Published: May 29, 2023

A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism.

A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism.

Journal: Nature metabolism

Published: March 30, 2023

PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.

PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.

Journal: Science advances

Published: December 09, 2022

Alpelisib administration reduced lymphatic malformations in a mouse model and in patients.

Alpelisib administration reduced lymphatic malformations in a mouse model and in patients.

Journal: Science translational medicine

Published: October 06, 2021

Author Correction: Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

Author Correction: Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

Journal: Nature

Published: April 05, 2019

Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

Journal: Nature

Published: March 01, 2017

Showing 1-12 of 13

Last Updated: 09/26/2026