Sophia M. Bruggeman

Groningen, GR, Netherlands

Last Updated: 09/26/2026

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Found 9 publications

Targeting the reprogrammed metabolism in H3.3K27M pediatric high-grade gliomas.

Targeting the reprogrammed metabolism in H3.3K27M pediatric high-grade gliomas.

Journal: Biochimica et biophysica acta. Molecular basis of disease
Published: February 23, 2024

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum.

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum.

Journal: International journal of molecular sciences
Published: July 25, 2022

The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.

The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.

Journal: Journal of cell science
Published: March 05, 2021

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.

Journal: PLoS genetics
Published: December 11, 2020

CREB signaling activity correlates with differentiation and survival in medulloblastoma.

CREB signaling activity correlates with differentiation and survival in medulloblastoma.

Journal: Scientific reports
Published: September 15, 2020

Heat shock factor 1 (HSF1-pSer326) predicts response to bortezomib-containing chemotherapy in pediatric AML: a COG report.

Heat shock factor 1 (HSF1-pSer326) predicts response to bortezomib-containing chemotherapy in pediatric AML: a COG report.

Journal: Blood
Published: April 13, 2020

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

Journal: Cell reports
Published: October 19, 2017

Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).

Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology
Published: June 15, 2017

Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.

Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.

Journal: Nature cell biology
Published: April 24, 2012
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Last Updated: 09/26/2026