Sophie B. Siems

Goettingen, NI, Germany

Last Updated: 09/26/2026

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Found 12 publications

CDC42-Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity.

CDC42-Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity.

Journal: Glia
Published: October 10, 2025

Developmental maturation and regional heterogeneity but no sexual dimorphism of the murine CNS myelin proteome.

Developmental maturation and regional heterogeneity but no sexual dimorphism of the murine CNS myelin proteome.

Journal: Glia
Published: June 20, 2024

Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.

Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.

Journal: Glia
Published: November 04, 2023

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

Journal: Nature neuroscience
Published: September 28, 2023

Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements.

Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements.

Journal: Nature communications
Published: July 24, 2023

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.

Journal: eLife
Published: January 12, 2022

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5.

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5.

Journal: eLife
Published: November 12, 2021

Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity.

Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity.

Journal: eLife
Published: May 28, 2021

Proteome Profile of Myelin in the Zebrafish Brain.

Proteome Profile of Myelin in the Zebrafish Brain.

Journal: Frontiers in cell and developmental biology
Published: December 10, 2020

The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay.

The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay.

Journal: Frontiers in cellular neuroscience
Published: May 14, 2020

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model.

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model.

Journal: eLife
Published: August 27, 2019

Turning to myelin turnover.

Turning to myelin turnover.

Journal: Neural regeneration research
Published: August 10, 2019
Showing 1-12 of 12

Last Updated: 09/26/2026