Sophie Crux

Bonn, NW, Germany

Last Updated: 09/26/2026

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Found 10 publications

CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser-Induced Lesions.

CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser-Induced Lesions.

Journal: Glia
Published: October 23, 2025

Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

Journal: Nature neuroscience
Published: July 01, 2024

Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes.

Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes.

Journal: Molecular psychiatry
Published: July 04, 2020

Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy.

Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy.

Journal: Acta neuropathologica
Published: August 05, 2019

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro.

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro.

Journal: eLife
Published: April 19, 2018

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.

Journal: Glia
Published: April 06, 2018

Tcf4 regulates dendritic spine density and morphology in the adult brain.

Tcf4 regulates dendritic spine density and morphology in the adult brain.

Journal: PloS one
Published: January 26, 2018

Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.

Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.

Journal: Biological psychiatry
Published: May 10, 2016

Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in Drosophila.

Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in Drosophila.

Journal: The Biochemical journal
Published: April 01, 2016

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis.

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis.

Journal: The EMBO journal
Published: February 10, 2016
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Last Updated: 09/26/2026