Sophie Durand-Lachau
Janssen R&D
Beerse, VLG, Belgium
Beerse, VLG, Belgium
Last Updated: 09/26/2026
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Found 11 publications
Safety, Tolerability, and Pharmacokinetics of JNJ-1802, a Pan-serotype Dengue Direct Antiviral Small Molecule, in a Phase 1, Double-Blind, Randomized, Dose-Escalation Study in Healthy Volunteers.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Published: January 12, 2023
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Journal: Nature
Published: June 29, 2022
Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery.
Journal: Advanced healthcare materials
Published: November 22, 2018
Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: July 11, 2018
Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and risk/benefit to patients.
Journal: PLoS neglected tropical diseases
Published: June 21, 2018
Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugia pahangi.
Journal: PLoS neglected tropical diseases
Published: February 09, 2018
Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds.
Journal: PLoS neglected tropical diseases
Published: January 17, 2018
Discovery of 1-((2R,4aR,6R,7R,7aR)-2-Isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2'-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione (JNJ-54257099), a 3'-5'-Cyclic Phosphate Ester Prodrug of 2'-Deoxy-2'-Spirooxetane Uridine Triphosphate Useful for HCV Inhibition.
Journal: Journal of medicinal chemistry
Published: May 17, 2016
Evaluation of Three Amorphous Drug Delivery Technologies to Improve the Oral Absorption of Flubendazole.
Journal: Journal of pharmaceutical sciences
Published: December 17, 2015
Nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as novel inhibitors of the HCV NS5B polymerase.
Journal: Journal of medicinal chemistry
Published: December 19, 2013
Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
Journal: Bioorganic & medicinal chemistry letters
Published: January 26, 2012
Showing 1-11 of 11
Last Updated: 09/26/2026