Sophie Keeling
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 9 publications
Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: October 16, 2025
Aggregate-selective removal of pathological tau by clustering-activated degraders.
Journal: Science (New York, N.Y.)
Published: August 29, 2024
Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons.
Journal: Molecular neurodegeneration
Published: January 23, 2024
The type-I interferon response potentiates seeded tau aggregation and exacerbates tau pathology.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: May 04, 2023
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.
Journal: Science (New York, N.Y.)
Published: March 30, 2023
Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion.
Journal: Nature chemical biology
Published: February 28, 2023
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding.
Journal: Cell reports
Published: October 31, 2022
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Journal: Cell reports
Published: September 24, 2021
Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional Biochemistry.
Journal: ACS chemical neuroscience
Published: August 25, 2020
Showing 1-9 of 9
Last Updated: 09/26/2026