Sophie Lestavel

Lille, 59000, France

Last Updated: 09/26/2026

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Found 30 publications

Intestinal FXR deficiency uncouples steatosis protection from liver inflammation and fibrosis in MASH-diet fed mice.

Intestinal FXR deficiency uncouples steatosis protection from liver inflammation and fibrosis in MASH-diet fed mice.

Journal: Scientific reports
Published: April 09, 2026

Endoplasmic reticulum-mitochondria contact sites are signalling hubs connecting nutrient sensing and GLP-1 secretion in L cells of the mouse gut: from physiology to obesity and type 2 diabetes.

Endoplasmic reticulum-mitochondria contact sites are signalling hubs connecting nutrient sensing and GLP-1 secretion in L cells of the mouse gut: from physiology to obesity and type 2 diabetes.

Journal: Diabetologia
Published: December 01, 2025

The farnesoid X receptor (FXR) antagonist 7β-isopropylchenodeoxycholic acid improves glucose metabolism in mice on a Western diet.

The farnesoid X receptor (FXR) antagonist 7β-isopropylchenodeoxycholic acid improves glucose metabolism in mice on a Western diet.

Journal: Pharmacological research
Published: May 07, 2025

Intestinal IncRNAs and circRNAs Regulated by Dietary-Lipid Stimuli.

Intestinal IncRNAs and circRNAs Regulated by Dietary-Lipid Stimuli.

Journal: Molecular nutrition & food research
Published: October 29, 2024

Corrigendum to "Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis" [Mol Metab 69 (2023) 1-13].

Corrigendum to "Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis" [Mol Metab 69 (2023) 1-13].

Journal: Molecular metabolism
Published: May 27, 2024

Genetic Evidence of Causal Relation Between Intestinal Glucose Absorption and Early Postprandial Glucose Response: A Mendelian Randomization Study.

Genetic Evidence of Causal Relation Between Intestinal Glucose Absorption and Early Postprandial Glucose Response: A Mendelian Randomization Study.

Journal: Diabetes
Published: October 09, 2023

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Journal: Journal of medicinal chemistry
Published: August 28, 2023

Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis.

Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis.

Journal: Molecular metabolism
Published: December 20, 2022

Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes.

Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes.

Journal: iScience
Published: September 12, 2022

Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System.

Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System.

Journal: Frontiers in molecular neuroscience
Published: November 03, 2021

An Exploratory Study of the Role of Dietary Proteins in the Regulation of Intestinal Glucose Absorption.

An Exploratory Study of the Role of Dietary Proteins in the Regulation of Intestinal Glucose Absorption.

Journal: Frontiers in nutrition
Published: September 29, 2021

Intestine-liver crosstalk in Type 2 Diabetes and non-alcoholic fatty liver disease.

Intestine-liver crosstalk in Type 2 Diabetes and non-alcoholic fatty liver disease.

Journal: Metabolism: clinical and experimental
Published: April 19, 2021
Showing 1-12 of 30

Last Updated: 09/26/2026