Sridhar Sreeramulu

Max Von Laue Str. 7
Frankfurt Am Main, HE 60438, Germany

Last Updated: 09/26/2026

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Found 57 publications

Fragment screening in focus.

Fragment screening in focus.

Journal: Structure (London, England : 1993)

Published: July 13, 2026

AI-assisted fragment-based drug discovery of SARS-CoV-2 macrodomain binders validated by NMR and X-ray crystallography.

AI-assisted fragment-based drug discovery of SARS-CoV-2 macrodomain binders validated by NMR and X-ray crystallography.

Journal: Communications chemistry

Published: January 21, 2026

Cupriavidus necator, an alternative source for isotopic enrichment of proteins expressed in insect cells for NMR investigations.

Cupriavidus necator, an alternative source for isotopic enrichment of proteins expressed in insect cells for NMR investigations.

Journal: Journal of biomolecular NMR

Published: December 23, 2025

Structure-Based Rational Design of a Selective Hydrolase Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus-2 Nsp3 Macrodomain.

Structure-Based Rational Design of a Selective Hydrolase Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus-2 Nsp3 Macrodomain.

Journal: Chembiochem : a European journal of chemical biology

Published: August 06, 2025

NMR screening of low molecular weight inhibitors targeting the papain-like protease (PLPro) of SARS-CoV-2.

NMR screening of low molecular weight inhibitors targeting the papain-like protease (PLPro) of SARS-CoV-2.

Journal: FEBS open bio

Published: March 19, 2025

Optimization of Structure-Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS-CoV-2.

Optimization of Structure-Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS-CoV-2.

Journal: Angewandte Chemie (International ed. in English)

Published: September 19, 2024

The future of integrated structural biology.

The future of integrated structural biology.

Journal: Structure (London, England : 1993)

Published: May 23, 2024

Differential effects of the N-terminal helix of FGF8b on the activity of a small-molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution.

Differential effects of the N-terminal helix of FGF8b on the activity of a small-molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution.

Journal: FEBS letters

Published: May 10, 2024

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Journal: ACS chemical biology

Published: January 17, 2024

Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection.

Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection.

Journal: RSC medicinal chemistry

Published: December 18, 2023

NMR characterization and ligand binding site of the stem-loop 2 motif from the Delta variant of SARS-CoV-2.

NMR characterization and ligand binding site of the stem-loop 2 motif from the Delta variant of SARS-CoV-2.

Journal: RNA (New York, N.Y.)

Published: November 27, 2023

Targeting EPHA2 with Kinase Inhibitors in Colorectal Cancer.

Targeting EPHA2 with Kinase Inhibitors in Colorectal Cancer.

Journal: ChemMedChem

Published: August 07, 2023

Showing 1-12 of 57

Last Updated: 09/26/2026