Stefan Carle

Unravelling the polysorbate 20 composition: A fusion of UPLC-MS analysis and stochastic modelling.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: June 19, 2025

All-in-one stability indicating polysorbate 20 degradation root-cause analytics via UPLC-QDa.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Published: September 22, 2023

How enzymatic hydrolysis of polysorbate 20 influences colloidal protein stability.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: May 13, 2023

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates.

Journal: Pharmaceutics

Published: October 20, 2022

Existence of a superior polysorbate fraction in respect to protein stabilization and particle formation?

Journal: International journal of pharmaceutics

Published: September 13, 2022

Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: May 13, 2021

Hydrolytic polysorbate 20 degradation - Sensitive detection of free fatty acids in biopharmaceuticals via UPLC-QDa analytics with isolator column.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Published: October 29, 2020

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80.

Journal: International journal of pharmaceutics

Published: July 17, 2020

Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro.

Journal: Archives of toxicology

Published: March 11, 2020

High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans.

Journal: Toxins

Published: November 07, 2017

Unravelling the polysorbate 20 composition: A fusion of UPLC-MS analysis and stochastic modelling.

Unravelling the polysorbate 20 composition: A fusion of UPLC-MS analysis and stochastic modelling.

All-in-one stability indicating polysorbate 20 degradation root-cause analytics via UPLC-QDa.

All-in-one stability indicating polysorbate 20 degradation root-cause analytics via UPLC-QDa.

How enzymatic hydrolysis of polysorbate 20 influences colloidal protein stability.

How enzymatic hydrolysis of polysorbate 20 influences colloidal protein stability.

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates.

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates.

Existence of a superior polysorbate fraction in respect to protein stabilization and particle formation?

Existence of a superior polysorbate fraction in respect to protein stabilization and particle formation?

Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions.

Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions.

Hydrolytic polysorbate 20 degradation - Sensitive detection of free fatty acids in biopharmaceuticals via UPLC-QDa analytics with isolator column.

Hydrolytic polysorbate 20 degradation - Sensitive detection of free fatty acids in biopharmaceuticals via UPLC-QDa analytics with isolator column.

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80.

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80.

Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro.

Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro.

Regulation of endo-lysosomal pathway and autophagic flux by broad-spectrum antipathogen inhibitor ABMA.

Regulation of endo-lysosomal pathway and autophagic flux by broad-spectrum antipathogen inhibitor ABMA.

Primary resistance of human patients to botulinum neurotoxins A and B.

Primary resistance of human patients to botulinum neurotoxins A and B.

High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans.

High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans.