Stefan Geschwindner

R&d
Goeteborg, O, Sweden

Last Updated: 09/26/2026

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Found 43 publications

Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naive Patients.

Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naive Patients.

Journal: Circulation

Published: May 15, 2026

Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naïve Patients.

Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naïve Patients.

Journal: Circulation

Published: May 15, 2026

Proximity Binding Assay for PROTAC Ternary Complex Analysis.

Proximity Binding Assay for PROTAC Ternary Complex Analysis.

Journal: ACS sensors

Published: April 21, 2026

Discovery of membrane channel modulators via DNA encoded library screening using native like membrane protein nanoparticles.

Discovery of membrane channel modulators via DNA encoded library screening using native like membrane protein nanoparticles.

Journal: Scientific reports

Published: March 09, 2026

Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognition.

Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognition.

Journal: bioRxiv : the preprint server for biology

Published: February 23, 2026

Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations.

Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2024

Robust Prediction of Relative Binding Energies for Protein-Protein Complex Mutations Using Free Energy Perturbation Calculations.

Robust Prediction of Relative Binding Energies for Protein-Protein Complex Mutations Using Free Energy Perturbation Calculations.

Journal: Journal of molecular biology

Published: April 25, 2024

An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA.

An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA.

Journal: RSC chemical biology

Published: May 19, 2023

Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction".

Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction".

Journal: Journal of medicinal chemistry

Published: January 26, 2023

Direct cell extraction of membrane proteins for structure-function analysis.

Direct cell extraction of membrane proteins for structure-function analysis.

Journal: Scientific reports

Published: July 15, 2022

Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.

Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.

Journal: Journal of medicinal chemistry

Published: February 02, 2022

Mining Natural Products for Macrocycles to Drug Difficult Targets.

Mining Natural Products for Macrocycles to Drug Difficult Targets.

Journal: Journal of medicinal chemistry

Published: December 18, 2020

Showing 1-12 of 43

Last Updated: 09/26/2026