Stefan J. Hammerschmidt

Mainz, RP 55128, Germany

Last Updated: 09/26/2026

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Found 23 publications

Next Generation of Fluorometric Protease Assays: 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-Amides) as Class-Spanning Protease Substrates.

Next Generation of Fluorometric Protease Assays: 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-Amides) as Class-Spanning Protease Substrates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: June 12, 2023

Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2.

Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2.

Journal: Communications chemistry

Published: April 12, 2023

Inhibitory effects of 190 compounds against SARS-CoV-2 Mpr o protein: Molecular docking interactions.

Inhibitory effects of 190 compounds against SARS-CoV-2 Mpr o protein: Molecular docking interactions.

Journal: Archiv der Pharmazie

Published: April 10, 2023

Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.

Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.

Journal: International journal of molecular sciences

Published: March 24, 2023

Improving binding entropy by higher ligand symmetry? - A case study with human matriptase.

Improving binding entropy by higher ligand symmetry? - A case study with human matriptase.

Journal: RSC medicinal chemistry

Published: March 16, 2023

The effects of allosteric and competitive inhibitors on ZIKV protease conformational dynamics explored through smFRET, nanoDSF, DSF, and 19F NMR.

The effects of allosteric and competitive inhibitors on ZIKV protease conformational dynamics explored through smFRET, nanoDSF, DSF, and 19F NMR.

Journal: European journal of medicinal chemistry

Published: February 13, 2023

Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors.

Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors.

Journal: European journal of medicinal chemistry

Published: November 08, 2022

Thermodynamic characterization of a macrocyclic Zika virus NS2B/NS3 protease inhibitor and its acyclic analogs.

Thermodynamic characterization of a macrocyclic Zika virus NS2B/NS3 protease inhibitor and its acyclic analogs.

Journal: Archiv der Pharmazie

Published: October 02, 2022

Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.

Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.

Journal: ACS medicinal chemistry letters

Published: July 21, 2022

A competition smFRET assay to study ligand-induced conformational changes of the dengue virus protease.

A competition smFRET assay to study ligand-induced conformational changes of the dengue virus protease.

Journal: Protein science : a publication of the Protein Society

Published: June 23, 2022

Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.

Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.

Journal: The Journal of antibiotics

Published: March 14, 2022

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Journal: ACS chemical biology

Published: March 09, 2022

Showing 1-12 of 23

Last Updated: 09/26/2026