Stefan Schmelz

Braunschweig, NI, Germany

Last Updated: 09/26/2026

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Found 29 publications

Structural and Biochemical Characterization of the Diaminopimelate Epimerase DapF From Pseudomonas aeruginosa PA14.

Structural and Biochemical Characterization of the Diaminopimelate Epimerase DapF From Pseudomonas aeruginosa PA14.

Journal: Proteins
Published: February 19, 2026

AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack.

AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack.

Journal: Molecular cell
Published: October 01, 2024

Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.

Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.

Journal: Cell host & microbe
Published: August 23, 2024

The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.

The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.

Journal: Science advances
Published: June 19, 2024

Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity.

Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity.

Journal: European journal of medicinal chemistry
Published: April 07, 2024

Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera.

Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera.

Journal: Nature communications
Published: January 11, 2024

The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.

The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.

Journal: Journal of virology
Published: June 08, 2023

Role of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Inflammation and Pathogen-Associated Interactions.

Role of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Inflammation and Pathogen-Associated Interactions.

Journal: Journal of innate immunity
Published: June 01, 2023

Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle.

Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: August 03, 2022

Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.

Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.

Journal: Nature communications
Published: April 14, 2022

Reproducible and Easy Production of Mammalian Proteins by Transient Gene Expression in High Five Insect Cells.

Reproducible and Easy Production of Mammalian Proteins by Transient Gene Expression in High Five Insect Cells.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: May 05, 2021

Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR.

Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR.

Journal: European journal of medicinal chemistry
Published: March 25, 2021
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Last Updated: 09/26/2026