Stefan Zielonka

Frankfurter Str. 250
Darmstadt, HE 64293, Germany

Last Updated: 09/26/2026

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Found 73 publications

Antibody framework engineering enables augmented cytokine receptor signaling capacities of bispecific single domain antibody-based IL-21 mimetics.

Antibody framework engineering enables augmented cytokine receptor signaling capacities of bispecific single domain antibody-based IL-21 mimetics.

Journal: mAbs

Published: September 02, 2026

Generation and Characterization of Bispecific VHH-Derived Surrogate Agonists Mimicking the Function of IL-18.

Generation and Characterization of Bispecific VHH-Derived Surrogate Agonists Mimicking the Function of IL-18.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: May 13, 2026

Protocol for in vitro profiling of key TNF downstream signaling pathways involved in cell death and pro-survival signaling in cancer cells.

Protocol for in vitro profiling of key TNF downstream signaling pathways involved in cell death and pro-survival signaling in cancer cells.

Journal: STAR protocols

Published: April 21, 2026

Multifunctional antibody-derived IL-12 mimetics: prospects of future clinical development.

Multifunctional antibody-derived IL-12 mimetics: prospects of future clinical development.

Journal: Expert opinion on investigational drugs

Published: January 04, 2026

Simultaneous targeting of IL-10 and PD-(L)1 pathways with a bispecific anti-PD-L1/IL-10-trap antibody enhances T cell responses.

Simultaneous targeting of IL-10 and PD-(L)1 pathways with a bispecific anti-PD-L1/IL-10-trap antibody enhances T cell responses.

Journal: Molecular therapy. Oncology

Published: November 06, 2025

From discovery to the clinic: structural insights, engineering options, clinical, and 'next wave' applications of camelid-derived single-domain antibodies.

From discovery to the clinic: structural insights, engineering options, clinical, and 'next wave' applications of camelid-derived single-domain antibodies.

Journal: mAbs

Published: November 05, 2025

Antigen-directed single domain antibody-based TNFR1 agonists elicit preferential killing of HER2-overexpressing cancer cells.

Antigen-directed single domain antibody-based TNFR1 agonists elicit preferential killing of HER2-overexpressing cancer cells.

Journal: iScience

Published: October 16, 2025

Optimizing colloidal stability and viscosity of multispecific antibodies at the drug discovery-development interface: a systematic predictive case study.

Optimizing colloidal stability and viscosity of multispecific antibodies at the drug discovery-development interface: a systematic predictive case study.

Journal: mAbs

Published: September 01, 2025

Trispecific SEED antibodies engineered for neutrophil-mediated cell killing.

Trispecific SEED antibodies engineered for neutrophil-mediated cell killing.

Journal: mAbs

Published: July 15, 2025

Targeting the major pro-inflammatory interleukin-6-type cytokine receptor gp130 by antagonistic single domain antibodies.

Targeting the major pro-inflammatory interleukin-6-type cytokine receptor gp130 by antagonistic single domain antibodies.

Journal: Frontiers in immunology

Published: April 16, 2025

Allosteric Antibody Modulation of EGFR Activity: Bridging Experiment and In Silico Modeling.

Allosteric Antibody Modulation of EGFR Activity: Bridging Experiment and In Silico Modeling.

Journal: Journal of molecular biology

Published: March 31, 2025

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities.

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities.

Journal: Protein science : a publication of the Protein Society

Published: October 22, 2024

Showing 1-12 of 73

Last Updated: 09/26/2026