Stefano A. Serapian

Via Taramelli 12
Pavia, 27100, Italy

Last Updated: 09/26/2026

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Found 43 publications

Post-Translational Modification as an Allosteric Switch in Hsp90: How Dual Phosphorylation Locks Chaperone Complexes into Hyperstabilized States.

Post-Translational Modification as an Allosteric Switch in Hsp90: How Dual Phosphorylation Locks Chaperone Complexes into Hyperstabilized States.

Journal: The journal of physical chemistry letters

Published: July 06, 2026

Molecular Dynamics Simulations Provide Further Insights into the Allosteric Regulation of the Kinesin-5 Motor Domain by Loop 5.

Molecular Dynamics Simulations Provide Further Insights into the Allosteric Regulation of the Kinesin-5 Motor Domain by Loop 5.

Journal: Journal of chemical information and modeling

Published: March 12, 2026

Phosphoryl Radicals from Trivalent Iminyl Phosphines: A Photocatalytic Approach to N-Phosphoryl Azetidines.

Phosphoryl Radicals from Trivalent Iminyl Phosphines: A Photocatalytic Approach to N-Phosphoryl Azetidines.

Journal: Angewandte Chemie (International ed. in English)

Published: February 25, 2026

In Vitro Anti-Glioblastoma Activity of a Novel Pt(IV)-Ganoderic Acid A Conjugate.

In Vitro Anti-Glioblastoma Activity of a Novel Pt(IV)-Ganoderic Acid A Conjugate.

Journal: International journal of molecular sciences

Published: February 25, 2026

New allosteric modulators of molecular chaperone TRAP1 from the integration of computational biology, medicinal chemistry, and biophysics.

New allosteric modulators of molecular chaperone TRAP1 from the integration of computational biology, medicinal chemistry, and biophysics.

Journal: Cell stress & chaperones

Published: February 13, 2026

Use of Computational Models to Investigate Human Targets of Small Ubiquitous Molecules.

Use of Computational Models to Investigate Human Targets of Small Ubiquitous Molecules.

Journal: Chembiochem : a European journal of chemical biology

Published: January 21, 2026

Hijacking client instability to selectively disrupt HSP90-driven glucocorticoid receptor activation.

Hijacking client instability to selectively disrupt HSP90-driven glucocorticoid receptor activation.

Journal: Pharmacological research

Published: January 19, 2026

Ligand-driven modulation of chaperone-cochaperone networks shapes proteostasis outcomes.

Ligand-driven modulation of chaperone-cochaperone networks shapes proteostasis outcomes.

Journal: Protein science : a publication of the Protein Society

Published: November 19, 2025

Density Functional Theory Calculations to Investigate the Role Played by an Aspartate Dyad in Hsp60-Catalyzed ATP Hydrolysis.

Density Functional Theory Calculations to Investigate the Role Played by an Aspartate Dyad in Hsp60-Catalyzed ATP Hydrolysis.

Journal: The journal of physical chemistry letters

Published: October 10, 2025

ATM kinase phosphorylates HSP90 on T297 changing its conformation dynamics and promoting its interaction with HER2 receptor tyrosine kinase.

ATM kinase phosphorylates HSP90 on T297 changing its conformation dynamics and promoting its interaction with HER2 receptor tyrosine kinase.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: April 15, 2025

Design of multi-target peptide modulators for protein chaperone networks.

Design of multi-target peptide modulators for protein chaperone networks.

Journal: Structure (London, England : 1993)

Published: February 28, 2025

Dehydrogenase versus oxidase function: the interplay between substrate binding and flavin microenvironment.

Dehydrogenase versus oxidase function: the interplay between substrate binding and flavin microenvironment.

Journal: ACS catalysis

Published: January 09, 2025

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Last Updated: 09/26/2026