Stefano Bartesaghi

AstraZeneca R&D
Goeteborg, O 43183, Sweden

Last Updated: 09/26/2026

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Found 22 publications

Inhibition of IL-33 in Diabetic Kidney Disease: A Randomized, Placebo-Controlled Phase 2b Trial.

Inhibition of IL-33 in Diabetic Kidney Disease: A Randomized, Placebo-Controlled Phase 2b Trial.

Journal: Journal of the American Society of Nephrology : JASN

Published: July 09, 2025

Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease.

Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease.

Journal: Kidney international reports

Published: February 07, 2024

NRF2 is essential for adaptative browning of white adipocytes.

NRF2 is essential for adaptative browning of white adipocytes.

Journal: Redox biology

Published: October 11, 2023

The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes.

The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes.

Journal: The Journal of biological chemistry

Published: March 01, 2023

SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation.

SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation.

Journal: Metabolism open

Published: October 07, 2022

Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

Journal: Diabetes

Published: March 28, 2022

Knockdown of sarcolipin (SLN) impairs substrate utilization in human skeletal muscle cells.

Knockdown of sarcolipin (SLN) impairs substrate utilization in human skeletal muscle cells.

Journal: Molecular biology reports

Published: November 18, 2021

Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice.

Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice.

Journal: Molecular therapy. Nucleic acids

Published: October 27, 2021

Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale.

Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale.

Journal: The Journal of cell biology

Published: October 25, 2021

Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immunostaining.

Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immunostaining.

Journal: RNA (New York, N.Y.)

Published: July 06, 2021

SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells.

SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells.

Journal: Current research in pharmacology and drug discovery

Published: June 18, 2021

Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.

Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.

Journal: Molecular therapy. Nucleic acids

Published: July 11, 2020

Showing 1-12 of 22

Last Updated: 09/26/2026