Stephen J. Tucker

Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 63 publications

Equivalent gain-of-function variants in KCNK3 and KCNK9 and their contribution to distinct TASK K2P channelopathies.

Equivalent gain-of-function variants in KCNK3 and KCNK9 and their contribution to distinct TASK K2P channelopathies.

Journal: The Journal of general physiology

Published: February 27, 2026

Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease.

Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease.

Journal: The EMBO journal

Published: August 07, 2025

Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels.

Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels.

Journal: Nature communications

Published: June 24, 2025

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel.

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel.

Journal: Journal of chemical theory and computation

Published: January 04, 2025

Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease.

Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease.

Journal: Structure (London, England : 1993)

Published: August 06, 2024

Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics.

Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics.

Journal: Nature structural & molecular biology

Published: July 19, 2024

Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.

Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.

Journal: Nature communications

Published: December 15, 2023

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel.

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel.

Journal: bioRxiv : the preprint server for biology

Published: November 28, 2023

Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels.

Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels.

Journal: Royal Society open science

Published: July 20, 2023

Correction: Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.

Correction: Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.

Journal: Physical chemistry chemical physics : PCCP

Published: July 17, 2023

Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.

Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts.

Journal: Physical chemistry chemical physics : PCCP

Published: June 27, 2023

Influence of electronic polarization on the binding of anions to a chloride-pumping rhodopsin.

Influence of electronic polarization on the binding of anions to a chloride-pumping rhodopsin.

Journal: Biophysical journal

Published: January 03, 2023

Showing 1-12 of 63

Last Updated: 09/26/2026