Stephen L. Lessnick

Hematology | Oncology
700 Childrens Dr # 5011
Columbus, OH 43205

Last Updated: 09/26/2026

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Found 69 publications

The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma.

The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma.

Journal: eLife
Published: June 15, 2026

DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma.

DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma.

Journal: bioRxiv : the preprint server for biology
Published: February 14, 2024

Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's Oncology Group.

Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's Oncology Group.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: January 20, 2023

Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.

Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.

Journal: British journal of cancer
Published: June 21, 2022

An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.

An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.

Journal: NPJ precision oncology
Published: March 01, 2022

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma.

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma.

Journal: Nucleic acids research
Published: January 12, 2022

Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.

Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.

Journal: Molecular cancer research : MCR
Published: January 11, 2022

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.

Journal: Nature cell biology
Published: November 14, 2021

Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins.

Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins.

Journal: Molecular cancer research : MCR
Published: May 23, 2021

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma.

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma.

Journal: PLoS computational biology
Published: February 03, 2021

Patterns of Translocation Testing in Patients Enrolling in a Cooperative Group Trial for Newly Diagnosed Metastatic Ewing Sarcoma.

Patterns of Translocation Testing in Patients Enrolling in a Cooperative Group Trial for Newly Diagnosed Metastatic Ewing Sarcoma.

Journal: Archives of pathology & laboratory medicine
Published: December 30, 2020

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.

Journal: Oncogene
Published: November 08, 2020
Showing 1-12 of 69

Last Updated: 09/26/2026