Steve M. Callaghan

Ottawa, ON, Canada

Last Updated: 09/26/2026

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Found 19 publications

A stress-dependent TDP-43 SUMOylation program preserves neuronal function.

A stress-dependent TDP-43 SUMOylation program preserves neuronal function.

Journal: Molecular neurodegeneration

Published: June 13, 2024

A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs.

A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs.

Journal: NPJ Parkinson's disease

Published: October 20, 2023

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy.

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy.

Journal: Cell death & disease

Published: July 18, 2023

Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain.

Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain.

Journal: iScience

Published: October 14, 2022

Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation.

Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation.

Journal: Human molecular genetics

Published: November 26, 2021

Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition.

Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition.

Journal: BMC biology

Published: August 03, 2021

Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.

Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.

Journal: Acta neuropathologica

Published: November 20, 2020

The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors.

The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors.

Journal: The Journal of biological chemistry

Published: February 12, 2019

DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress.

DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress.

Journal: Cell death & disease

Published: May 17, 2018

Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease.

Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 16, 2018

Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP.

Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP.

Journal: Journal of neurochemistry

Published: April 19, 2018

Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo.

Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: September 27, 2016

Showing 1-12 of 19

Last Updated: 09/26/2026