Steven C. Ley

London, ENG NW32PP, United Kingdom

Last Updated: 09/26/2026

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Found 34 publications

CARD14 signaling in intestinal epithelial cells induces intestinal inflammation and intestinal transit delay.

CARD14 signaling in intestinal epithelial cells induces intestinal inflammation and intestinal transit delay.

Journal: EMBO molecular medicine

Published: April 10, 2025

Bioinformatic analysis of molecular characteristics and oncogenic features of CARD14 in human cancer.

Bioinformatic analysis of molecular characteristics and oncogenic features of CARD14 in human cancer.

Journal: Scientific reports

Published: April 22, 2024

CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation.

CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation.

Journal: The Biochemical journal

Published: February 14, 2024

p38γ and p38δ modulate innate immune response by regulating MEF2D activation.

p38γ and p38δ modulate innate immune response by regulating MEF2D activation.

Journal: eLife

Published: January 15, 2023

Correction: TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages.

Correction: TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages.

Journal: Journal of cell science

Published: November 03, 2022

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages.

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: March 09, 2021

TPL-2 kinase induces phagosome acidification to promote macrophage killing of bacteria.

TPL-2 kinase induces phagosome acidification to promote macrophage killing of bacteria.

Journal: The EMBO journal

Published: July 08, 2020

CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation.

CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation.

Journal: eLife

Published: March 07, 2020

ABIN-2, of the TPL-2 Signaling Complex, Modulates Mammalian Inflammation.

ABIN-2, of the TPL-2 Signaling Complex, Modulates Mammalian Inflammation.

Journal: Trends in immunology

Published: April 04, 2019

Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate.

Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate.

Journal: The Biochemical journal

Published: July 20, 2017

Protein CoAlation: a redox-linked post-translational modification.

Protein CoAlation: a redox-linked post-translational modification.

Journal: The Biochemical journal

Published: June 23, 2017

A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation.

A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation.

Journal: The Journal of experimental medicine

Published: May 24, 2017

Showing 1-12 of 34

Last Updated: 09/26/2026