Last Updated: 09/26/2026
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Found 16 publications
A brain-penetrant P2X7R antagonist mitigates Alzheimer's disease pathology.
Journal: bioRxiv : the preprint server for biology
Published: April 17, 2026
Methodological guidelines for P2X receptor assays and data interpretation.
Journal: Cell death & disease
Published: January 18, 2026
Giant pulmonary artery masquerading as pneumonia.
Journal: BMJ case reports
Published: October 23, 2025
Subtype-specific structural features of the hearing loss-associated human P2X2 receptor.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 12, 2025
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.
Journal: Science advances
Published: January 17, 2025
A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor.
Journal: Nature communications
Published: December 17, 2024
P2X7 receptors exhibit at least three modes of allosteric antagonism.
Journal: Science advances
Published: October 04, 2024
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.
Journal: bioRxiv : the preprint server for biology
Published: August 30, 2024
Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding.
Journal: Nature communications
Published: June 03, 2024
High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket.
Journal: Nature communications
Published: January 07, 2024
How Structural Biology Has Directly Impacted Our Understanding of P2X Receptor Function and Gating.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: July 01, 2022
Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology.
Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology.
Journal: Frontiers in pharmacology
Published: April 22, 2022
Last Updated: 09/26/2026