Steven G. Harper

Steven G. Harper

Colorectal Surgery

1235 Old York Road
Levy Medical Plaza Suite G20
Abington, PA 19001

Last Updated: 09/26/2026

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Found 22 publications

Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.

Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.

Journal: Journal of medicinal chemistry

Published: December 15, 2020

NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model.

NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model.

Journal: Free radical biology & medicine

Published: August 07, 2020

Optimization of 2-(1H-imidazo-2-yl)piperazines series of Trypanosoma brucei growth inhibitors as potential treatment for the second stage of HAT.

Optimization of 2-(1H-imidazo-2-yl)piperazines series of Trypanosoma brucei growth inhibitors as potential treatment for the second stage of HAT.

Journal: Bioorganic & medicinal chemistry letters

Published: February 24, 2020

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: January 13, 2020

Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme.

Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme.

Journal: PLoS neglected tropical diseases

Published: December 19, 2019

5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein.

5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein.

Journal: ACS medicinal chemistry letters

Published: December 16, 2019

Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.

Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.

Journal: ACS medicinal chemistry letters

Published: December 11, 2019

Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors.

Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors.

Journal: Scientific reports

Published: May 24, 2019

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.

Journal: ACS medicinal chemistry letters

Published: October 31, 2018

Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.

Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.

Journal: Bioorganic & medicinal chemistry letters

Published: September 25, 2018

Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening.

Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening.

Journal: PLoS neglected tropical diseases

Published: June 19, 2018

Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins.

Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins.

Journal: Bioorganic & medicinal chemistry letters

Published: December 22, 2017

Showing 1-12 of 22

Last Updated: 09/26/2026