Last Updated: 09/26/2026
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Found 13 publications
Femoral Vascular Closure Devices and Bleeding, Hemostasis, and Ambulation Following Percutaneous Coronary Intervention.
Journal: Journal of the American Heart Association
Published: December 30, 2022
Interplay between PCI access site, anticoagulant agent, and bleeding: Insights from the REGULATE-PCI randomized trial.
Journal: American heart journal
Published: November 02, 2019
Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.
Journal: Cardiovascular drugs and therapy
Published: July 24, 2017
Direct factor IXa inhibition with the RNA-aptamer pegnivacogin reduces platelet reactivity in vitro and residual platelet aggregation in patients with acute coronary syndromes.
Journal: European heart journal. Acute cardiovascular care
Published: April 14, 2017
Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer.
Journal: The Journal of allergy and clinical immunology
Published: December 04, 2015
Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial.
Journal: Lancet (London, England)
Published: November 09, 2015
Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer.
Journal: The Journal of allergy and clinical immunology
Published: June 22, 2015
Inhibition of factor IXa by the pegnivacogin system during cardiopulmonary bypass: a potential substitute for heparin. A study in baboons.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Published: January 20, 2015
Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention: results from the phase II RADAR-PCI study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Published: June 16, 2014
The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study.
Journal: Journal of thrombosis and thrombolysis
Published: June 02, 2014
Safety of very early sheath removal in patients treated with REG1 for acute coronary syndromes: insights from the RADAR trial.
Journal: The Journal of invasive cardiology
Published: November 05, 2013
Last Updated: 09/26/2026