Last Updated: 09/26/2026
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Found 73 publications
Pharmacokinetic and biodistribution (PK/BD) study of ProGel-Dex, a thermoresponsive dexamethasone prodrug for sustained joint pain relief in a mouse model of osteoarthritis.
Journal: Nanomedicine : nanotechnology, biology, and medicine
Published: August 29, 2025
Intradermal Injection of a Thermoresponsive Polymeric Dexamethasone Prodrug (ProGel-Dex) Ameliorate Dermatitis in an Imiquimod (IMQ)-Induced Psoriasis-like Mouse Model.
Journal: Molecular pharmaceutics
Published: September 03, 2024
Joint damage is more severe following a single bout than multiple bouts of high magnitude loading in mice.
Journal: Osteoarthritis and cartilage
Published: July 09, 2024
Identification of formulation parameters that affect the analgesic efficacy of ProGel-Dex - A thermoresponsive polymeric dexamethasone prodrug for chronic arthritis pain relief.
Journal: Nanomedicine : nanotechnology, biology, and medicine
Published: June 19, 2024
PTH treatment before cyclic joint loading improves cartilage health and attenuates load-induced osteoarthritis development in mice.
Journal: Science advances
Published: April 19, 2024
Thermoresponsive Polymeric Hydromorphone Prodrug Provides Sustained Local Analgesia without Apparent Adverse Effects.
Journal: Molecular pharmaceutics
Published: February 27, 2024
Single dose thermoresponsive dexamethasone prodrug completely mitigates joint pain for 15 weeks in a murine model of osteoarthritis.
Journal: Nanomedicine : nanotechnology, biology, and medicine
Published: November 12, 2023
Macroscopic Synovial Inflammation Correlates with Symptoms and Cartilage Lesions in Patients Undergoing Arthroscopic Partial Meniscectomy: A Clinical Study.
Journal: Journal of clinical medicine
Published: April 29, 2022
Contribution of joint tissue properties to load-induced osteoarthritis.
Journal: Bone reports
Published: March 13, 2022
Do Synovial Inflammation and Meniscal Degeneration Impact Clinical Outcomes of Patients Undergoing Arthroscopic Partial Meniscectomy? A Histological Study.
Journal: International journal of molecular sciences
Published: March 04, 2022
Polymeric dexamethasone prodrugs attenuate lupus nephritis in MRL/lpr mice with reduced glucocorticoid toxicity.
Journal: Nanomedicine : nanotechnology, biology, and medicine
Published: January 14, 2022
Preclinical Dose-Escalation Study of ZSJ-0228, a Polymeric Dexamethasone Prodrug, in the Treatment of Murine Lupus Nephritis.
Journal: Molecular pharmaceutics
Published: September 27, 2021
Last Updated: 09/26/2026