Suling Huang

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 15 publications

SIK1 drives lipid-induced insulin resistance in skeletal muscle by linking TGFβ1-Smad2/3 activation to PDE4-cAMP dysregulation.

SIK1 drives lipid-induced insulin resistance in skeletal muscle by linking TGFβ1-Smad2/3 activation to PDE4-cAMP dysregulation.

Journal: Molecular and cellular endocrinology

Published: February 03, 2026

Cassane diterpenoids with hepatic gluconeogenesis inhibitory activity from the seeds of Caesalpinia decapetala (Roth) Alston.

Cassane diterpenoids with hepatic gluconeogenesis inhibitory activity from the seeds of Caesalpinia decapetala (Roth) Alston.

Journal: Phytochemistry

Published: January 21, 2025

Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocation.

Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocation.

Journal: Natural products and bioprospecting

Published: December 17, 2024

Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis.

Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis.

Journal: Bioorganic chemistry

Published: September 11, 2024

Clerodane diterpenoids from the vine stems of Fibraurea recisa Pierre and their hepatic gluconeogenesis inhibitory activity.

Clerodane diterpenoids from the vine stems of Fibraurea recisa Pierre and their hepatic gluconeogenesis inhibitory activity.

Journal: Phytochemistry

Published: August 07, 2024

Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM).

Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM).

Journal: European journal of medicinal chemistry

Published: October 14, 2022

Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice.

Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice.

Journal: Nutrients

Published: May 09, 2022

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.

Journal: Clinical science (London, England : 1979)

Published: June 08, 2021

Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid.

Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid.

Journal: Metabolites

Published: May 08, 2021

An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19.

An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19.

Journal: Signal transduction and targeted therapy

Published: September 26, 2020

TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.

TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.

Journal: Metabolism: clinical and experimental

Published: March 13, 2019

Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3.

Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3.

Journal: Frontiers in pharmacology

Published: November 15, 2017

Showing 1-12 of 15

Last Updated: 09/26/2026