Sun Huang
3330 Hospital Drive NW
Hotchkiss, AB T2N4N1, Canada
Hotchkiss, AB T2N4N1, Canada
Last Updated: 09/26/2026
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Found 21 publications
Design and optimization of nafimidone-inspired hybrid scaffolds targeting NaV1.2 for antiepileptic therapy with reduced cardiac liability.
Journal: Bioorganic chemistry
Published: July 05, 2026
Cav3.2 channels modulate allodynia but TRP channels are the primary mediators in prenatal valproic acid-induced sensory dysfunction.
Journal: Neuroscience
Published: September 23, 2025
Pharmacological inhibition of NaV1.8 by suzetrigine reveals potent analgesic potential without tolerance development in mice.
Journal: Molecular brain
Published: September 09, 2025
Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity.
Journal: Drug development research
Published: June 23, 2025
CaV3.2 T-type calcium channels contribute to CGRP- induced allodynia in a rodent model of experimental migraine.
Journal: The journal of headache and pain
Published: October 29, 2024
A pathological missense mutation in the deubiquitinase USP5 leads to insensitivity to pain.
Journal: The Journal of experimental medicine
Published: October 10, 2024
Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids acting as dual T-type CCB/MMP-9 inhibitors.
Journal: Journal of enzyme inhibition and medicinal chemistry
Published: August 14, 2024
Biginelli dihydropyrimidines and their acetylated derivatives as L-/T-type calcium channel blockers: Synthesis, enantioseparation, and molecular modeling studies.
Journal: Archiv der Pharmazie
Published: July 16, 2024
Effect of ABT-639 on Cav3.2 channel activity and its analgesic actions in mouse models of inflammatory and neuropathic pain.
Journal: European journal of pharmacology
Published: December 01, 2023
Icariside II, a Prenyl-Flavonol, Alleviates Inflammatory and Neuropathic Pain by Inhibiting T-Type Calcium Channels and USP5-Cav3.2 Interactions.
Journal: ACS chemical neuroscience
Published: April 28, 2023
Differential regulation of Cav 3.2 and Cav 2.2 calcium channels by CB1 receptors and cannabidiol.
Journal: British journal of pharmacology
Published: September 07, 2022
Focusing on C-4 position of Hantzsch 1,4-dihydropyridines: Molecular modifications, enantioseparation, and binding mechanism to L- and T-type calcium channels.
Journal: European journal of medicinal chemistry
Published: July 17, 2022
Last Updated: 09/26/2026