Supreeth Guptha

Bellary Road
Bengaluru, KA 560024, India

Last Updated: 09/26/2026

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Found 16 publications

Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity.

Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity.

Journal: ACS medicinal chemistry letters
Published: July 29, 2019

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.

Journal: Journal of medicinal chemistry
Published: January 12, 2017

Unravelling the Secrets of Mycobacterial Cidality through the Lens of Antisense.

Unravelling the Secrets of Mycobacterial Cidality through the Lens of Antisense.

Journal: PloS one
Published: January 06, 2016

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity.

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity.

Journal: ChemMedChem
Published: October 08, 2015

Whole cell screen based identification of spiropiperidines with potent antitubercular properties.

Whole cell screen based identification of spiropiperidines with potent antitubercular properties.

Journal: Bioorganic & medicinal chemistry letters
Published: March 14, 2015

Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.

Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.

Journal: Tuberculosis (Edinburgh, Scotland)
Published: February 11, 2015

UDP-N-acetylmuramic acid l-alanine ligase (MurC) inhibition in a tolC mutant Escherichia coli strain leads to cell death.

UDP-N-acetylmuramic acid l-alanine ligase (MurC) inhibition in a tolC mutant Escherichia coli strain leads to cell death.

Journal: Antimicrobial agents and chemotherapy
Published: August 13, 2014

Pyrazolopyrimidines establish MurC as a vulnerable target in Pseudomonas aeruginosa and Escherichia coli.

Pyrazolopyrimidines establish MurC as a vulnerable target in Pseudomonas aeruginosa and Escherichia coli.

Journal: ACS chemical biology
Published: July 19, 2014

Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.

Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.

Journal: Journal of medicinal chemistry
Published: June 27, 2014

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

Journal: Journal of medicinal chemistry
Published: May 30, 2014

Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.

Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.

Journal: Journal of medicinal chemistry
Published: May 14, 2014

2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis.

2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis.

Journal: ACS medicinal chemistry letters
Published: May 13, 2014
Showing 1-12 of 16

Last Updated: 09/26/2026