Susanna Cogoi

Udine, 33100, Italy

Last Updated: 09/26/2026

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Found 14 publications

RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation.

RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation.

Journal: Journal of medicinal chemistry
Published: November 16, 2017

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription.

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription.

Journal: Nucleic acids research
Published: June 05, 2017

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.

Journal: Biochimica et biophysica acta. General subjects
Published: October 14, 2016

Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles: delivery and bioactivity in pancreatic cancer cells.

Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles: delivery and bioactivity in pancreatic cancer cells.

Journal: Scientific reports
Published: May 12, 2016

Photosensitizers binding to nucleic acids as anticancer agents.

Photosensitizers binding to nucleic acids as anticancer agents.

Journal: Future medicinal chemistry
Published: January 26, 2016

G4 DNA in ras genes and its potential in cancer therapy.

G4 DNA in ras genes and its potential in cancer therapy.

Journal: Biochimica et biophysica acta
Published: November 09, 2015

GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1.

GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1.

Journal: Scientific reports
Published: August 19, 2015

Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism.

Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism.

Journal: ACS medicinal chemistry letters
Published: August 04, 2015

Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells.

Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells.

Journal: Journal of medicinal chemistry
Published: June 10, 2015

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property.

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property.

Journal: Nucleic acids research
Published: July 12, 2014

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies.

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies.

Journal: Molecular cancer
Published: September 26, 2013

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.

Journal: Nucleic acids research
Published: March 09, 2013
Showing 1-12 of 14

Last Updated: 09/26/2026