Susanna M. Kemppainen

Kuopio, Finland

Last Updated: 09/26/2026

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Found 19 publications

Intracerebroventricular phospho-tau immunotherapy alleviates cortical phospho-tau burden and motor phenotype in a neuron-specific P301S tauopathy mouse.

Intracerebroventricular phospho-tau immunotherapy alleviates cortical phospho-tau burden and motor phenotype in a neuron-specific P301S tauopathy mouse.

Journal: Experimental neurology
Published: January 27, 2025

The protective PLCγ2-P522R variant mitigates Alzheimer's disease-associated pathologies by enhancing beneficial microglial functions.

The protective PLCγ2-P522R variant mitigates Alzheimer's disease-associated pathologies by enhancing beneficial microglial functions.

Journal: Journal of neuroinflammation
Published: November 21, 2024

Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome.

Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome.

Journal: Journal of neuropathology and experimental neurology
Published: August 05, 2024

Physiological shedding and C-terminal proteolytic processing of TMEM106B.

Physiological shedding and C-terminal proteolytic processing of TMEM106B.

Journal: Cell reports
Published: June 17, 2024

Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates.

Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates.

Journal: Cells
Published: April 21, 2023

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models.

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models.

Journal: Neurobiology of disease
Published: February 23, 2023

Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men.

Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men.

Journal: Metabolites
Published: December 16, 2021

MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation.

MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation.

Journal: Cells
Published: March 01, 2021

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.

Journal: Molecular neurodegeneration
Published: April 28, 2020

Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway.

Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway.

Journal: Frontiers in neuroscience
Published: February 27, 2019

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease.

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease.

Journal: Frontiers in neuroscience
Published: September 28, 2018

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.

Journal: Neurobiology of aging
Published: July 13, 2018
Showing 1-12 of 19

Last Updated: 09/26/2026