Sussan Ghassabian

St Lucia Campus
Brisbane, QLD 4072, Australia

Last Updated: 09/26/2026

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Found 30 publications

In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes.

In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes.

Journal: European journal of drug metabolism and pharmacokinetics

Published: April 16, 2023

CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats.

CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats.

Journal: Pharmacological reports : PR

Published: October 05, 2022

Cough as an adverse effect on inhalation pharmaceutical products.

Cough as an adverse effect on inhalation pharmaceutical products.

Journal: British journal of pharmacology

Published: March 13, 2020

Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine.

Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine.

Journal: European journal of pharmacology

Published: July 26, 2019

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy.

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy.

Journal: Methods and protocols

Published: February 25, 2019

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement.

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: December 18, 2018

An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity.

An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity.

Journal: Bioanalysis

Published: September 19, 2018

Sorafenib N-Oxide Is an Inhibitor of Human Hepatic CYP3A4.

Sorafenib N-Oxide Is an Inhibitor of Human Hepatic CYP3A4.

Journal: The AAPS journal

Published: July 19, 2018

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.

Journal: Angewandte Chemie (International ed. in English)

Published: July 06, 2018

Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy.

Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy.

Journal: Drug metabolism reviews

Published: December 20, 2017

Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression.

Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression.

Journal: Neuropharmacology

Published: July 25, 2017

An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma.

An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Published: July 20, 2017

Showing 1-12 of 30

Last Updated: 09/26/2026