Suvarna H. Pagire

Gwangju, Republic of Korea

Last Updated: 09/26/2026

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Found 19 publications

Inhibition of HTR2B-mediated serotonin signaling in colorectal cancer suppresses tumor growth through ERK signaling.

Inhibition of HTR2B-mediated serotonin signaling in colorectal cancer suppresses tumor growth through ERK signaling.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 23, 2024

PDK4-mediated metabolic reprogramming is a potential therapeutic target for neovascular age-related macular degeneration.

PDK4-mediated metabolic reprogramming is a potential therapeutic target for neovascular age-related macular degeneration.

Journal: Cell death & disease

Published: April 19, 2024

Activation mechanism and novel binding sites of the BKCa channel activator CTIBD.

Activation mechanism and novel binding sites of the BKCa channel activator CTIBD.

Journal: Life science alliance

Published: January 26, 2024

Discovery of a peripheral 5HT2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis.

Discovery of a peripheral 5HT2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis.

Journal: Nature communications

Published: February 26, 2023

Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion.

Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion.

Journal: Kidney international

Published: August 07, 2022

Identification of New Non-BBB Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty Liver Disease.

Identification of New Non-BBB Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty Liver Disease.

Journal: Molecules (Basel, Switzerland)

Published: March 31, 2022

Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation.

Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation.

Journal: Cellular and molecular gastroenterology and hepatology

Published: March 17, 2022

Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT2A receptor antagonists for nonalcoholic fatty liver disease.

Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT2A receptor antagonists for nonalcoholic fatty liver disease.

Journal: European journal of medicinal chemistry

Published: January 13, 2022

Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease.

Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease.

Journal: Journal of medicinal chemistry

Published: January 08, 2021

Identification and Characterization of a Novel Large-Conductance Calcium-Activated Potassium Channel Activator, CTIBD, and Its Relaxation Effect on Urinary Bladder Smooth Muscle.

Identification and Characterization of a Novel Large-Conductance Calcium-Activated Potassium Channel Activator, CTIBD, and Its Relaxation Effect on Urinary Bladder Smooth Muscle.

Journal: Molecular pharmacology

Published: June 30, 2020

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease.

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease.

Journal: Journal of medicinal chemistry

Published: April 15, 2020

TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation.

TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation.

Journal: Nature communications

Published: September 17, 2019

Showing 1-12 of 19

Last Updated: 09/26/2026