Sylvain Lengacher

Geneve, GE 1202, Switzerland

Last Updated: 09/26/2026

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Found 19 publications

GLUT1-DS Brain Organoids Exhibit Increased Sensitivity to Metabolic and Pharmacological Induction of Epileptiform Activity.

GLUT1-DS Brain Organoids Exhibit Increased Sensitivity to Metabolic and Pharmacological Induction of Epileptiform Activity.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: November 21, 2025

Epileptiform activity in brain organoids derived from patient with Glucose Transporter 1 Deficiency Syndrome.

Epileptiform activity in brain organoids derived from patient with Glucose Transporter 1 Deficiency Syndrome.

Journal: Frontiers in neuroscience

Published: September 19, 2024

Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives.

Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives.

Journal: Frontiers in physiology

Published: November 30, 2021

Ganglioside GM1 Targets Astrocytes to Stimulate Cerebral Energy Metabolism.

Ganglioside GM1 Targets Astrocytes to Stimulate Cerebral Energy Metabolism.

Journal: Frontiers in pharmacology

Published: January 15, 2021

Hyperpolarized 13C Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of l-Lactate in Vivo.

Hyperpolarized 13C Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of l-Lactate in Vivo.

Journal: ACS chemical neuroscience

Published: May 18, 2018

Extracellular Potassium and Glutamate Interact To Modulate Mitochondria in Astrocytes.

Extracellular Potassium and Glutamate Interact To Modulate Mitochondria in Astrocytes.

Journal: ACS chemical neuroscience

Published: May 10, 2018

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Journal: Advances in experimental medicine and biology

Published: May 04, 2018

Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation.

Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 13, 2016

Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases.

Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases.

Journal: Current pharmaceutical design

Published: May 23, 2015

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.

Journal: Cell metabolism

Published: May 21, 2015

Learning-Induced Gene Expression in the Hippocampus Reveals a Role of Neuron -Astrocyte Metabolic Coupling in Long Term Memory.

Learning-Induced Gene Expression in the Hippocampus Reveals a Role of Neuron -Astrocyte Metabolic Coupling in Long Term Memory.

Journal: PloS one

Published: May 05, 2015

Channel-mediated lactate release by K⁺-stimulated astrocytes.

Channel-mediated lactate release by K⁺-stimulated astrocytes.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: March 13, 2015

Showing 1-12 of 19

Last Updated: 09/26/2026