Sylvia De Brakeleer

Brussels, BRU 1090, Belgium

Last Updated: 09/26/2026

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Found 12 publications

Identification of RAD17 as a candidate cancer predisposition gene in families with histories of pancreatic and breast cancers.

Identification of RAD17 as a candidate cancer predisposition gene in families with histories of pancreatic and breast cancers.

Journal: BMC cancer
Published: June 20, 2023

The genomic landscape of nonsmall cell lung carcinoma in never smokers.

The genomic landscape of nonsmall cell lung carcinoma in never smokers.

Journal: International journal of cancer
Published: March 28, 2019

Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families.

Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families.

Journal: BMC cancer
Published: August 28, 2018

CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition.

CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition.

Journal: Oncogene
Published: June 18, 2018

Type II RAF inhibitor causes superior ERK pathway suppression compared to type I RAF inhibitor in cells expressing different BRAF mutant types recurrently found in lung cancer.

Type II RAF inhibitor causes superior ERK pathway suppression compared to type I RAF inhibitor in cells expressing different BRAF mutant types recurrently found in lung cancer.

Journal: Oncotarget
Published: April 19, 2017

An alternative model for (breast) cancer predisposition.

An alternative model for (breast) cancer predisposition.

Journal: NPJ breast cancer
Published: August 19, 2016

Biomarker Analysis in a Phase II Study of Sunitinib in Patients with Advanced Melanoma.

Biomarker Analysis in a Phase II Study of Sunitinib in Patients with Advanced Melanoma.

Journal: Anticancer research
Published: December 06, 2015

Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.

Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.

Journal: Oncotarget
Published: October 08, 2015

Detection of EGFR-TK domain-activating mutations in NSCLC with generic PCR-based methods.

Detection of EGFR-TK domain-activating mutations in NSCLC with generic PCR-based methods.

Journal: Applied immunohistochemistry & molecular morphology : AIMM
Published: March 10, 2015

Frequent incidence of BARD1-truncating mutations in germline DNA from triple-negative breast cancer patients.

Frequent incidence of BARD1-truncating mutations in germline DNA from triple-negative breast cancer patients.

Journal: Clinical genetics
Published: February 19, 2015

Systematic detection of pathogenic alu element insertions in NGS-based diagnostic screens: the BRCA1/BRCA2 example.

Systematic detection of pathogenic alu element insertions in NGS-based diagnostic screens: the BRCA1/BRCA2 example.

Journal: Human mutation
Published: August 22, 2012

Correlation of EGFR, IDH1 and PTEN status with the outcome of patients with recurrent glioblastoma treated in a phase II clinical trial with the EGFR-blocking monoclonal antibody cetuximab.

Correlation of EGFR, IDH1 and PTEN status with the outcome of patients with recurrent glioblastoma treated in a phase II clinical trial with the EGFR-blocking monoclonal antibody cetuximab.

Journal: International journal of oncology
Published: March 09, 2012
Showing 1-12 of 12

Last Updated: 09/26/2026