Sylvia F. Boj

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 50 publications

Author Correction: Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.

Author Correction: Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.

Journal: Nature cell biology

Published: July 31, 2026

Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli.

Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli.

Journal: Journal of medicinal chemistry

Published: August 26, 2025

Accelerating personalized medicine: miniaturized patient-derived organoid drug screening for predicting cancer treatment responses and beyond.

Accelerating personalized medicine: miniaturized patient-derived organoid drug screening for predicting cancer treatment responses and beyond.

Journal: npj biomedical innovations

Published: June 24, 2025

Patient-Derived Organoids Predict Treatment Response in Metastatic Colorectal Cancer.

Patient-Derived Organoids Predict Treatment Response in Metastatic Colorectal Cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: May 18, 2025

A compendium of next-generation patient-derived models for diverse cancers.

A compendium of next-generation patient-derived models for diverse cancers.

Journal: Nature

Published: February 08, 2025

Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis.

Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Published: January 25, 2024

Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study.

Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Published: January 12, 2024

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.

Journal: Journal of experimental & clinical cancer research : CR

Published: December 20, 2023

Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules.

Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: January 30, 2023

Engineering multicellular living systems-a Keystone Symposia report.

Engineering multicellular living systems-a Keystone Symposia report.

Journal: Annals of the New York Academy of Sciences

Published: September 30, 2022

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.

Journal: Journal for immunotherapy of cancer

Published: September 30, 2022

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier.

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier.

Journal: Inflammatory bowel diseases

Published: July 11, 2022

Showing 1-12 of 50

Last Updated: 09/26/2026