Sylvia Merkert

Hannover, NI 30625, Germany

Last Updated: 09/26/2026

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Found 40 publications

Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease.

Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease.

Journal: Stem cell research & therapy
Published: July 22, 2025

Human CFTR deficient iPSC-macrophages reveal impaired functional and transcriptomic response upon Pseudomonas aeruginosa infection.

Human CFTR deficient iPSC-macrophages reveal impaired functional and transcriptomic response upon Pseudomonas aeruginosa infection.

Journal: Frontiers in immunology
Published: March 08, 2024

An Improved Protocol for Targeted Differentiation of Primed Human Induced Pluripotent Stem Cells into HLA-G-Expressing Trophoblasts to Enable the Modeling of Placenta-Related Disorders.

An Improved Protocol for Targeted Differentiation of Primed Human Induced Pluripotent Stem Cells into HLA-G-Expressing Trophoblasts to Enable the Modeling of Placenta-Related Disorders.

Journal: Cells
Published: June 13, 2023

Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing.

Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing.

Journal: Stem cell research
Published: March 02, 2023

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner.

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner.

Journal: PLoS pathogens
Published: January 18, 2023

Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line.

Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line.

Journal: Stem cell research
Published: July 08, 2022

ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives.

ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives.

Journal: Clinical and translational medicine
Published: March 15, 2022

Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies.

Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies.

Journal: Molecular therapy. Methods & clinical development
Published: December 17, 2021

Generation of human induced pluripotent stem cell lines encoding for genetically encoded calcium indicators RCaMP1h and GCaMP6f.

Generation of human induced pluripotent stem cell lines encoding for genetically encoded calcium indicators RCaMP1h and GCaMP6f.

Journal: Stem cell research
Published: December 08, 2021

Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in exon 11 of the BMPR2 gene.

Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in exon 11 of the BMPR2 gene.

Journal: Stem cell research
Published: June 25, 2021

Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation in the MYH7 gene.

Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation in the MYH7 gene.

Journal: Stem cell research
Published: November 05, 2020

Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing.

Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing.

Journal: Stem cell research
Published: October 30, 2020
Showing 1-12 of 40

Last Updated: 09/26/2026