Sylvie Claeysen

Montpellier, France

Last Updated: 09/26/2026

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Found 34 publications

Combining β2-AR agonism with butyrylcholinesterase inhibition, a synergistic neuroprotective action against Alzheimer's disease.

Combining β2-AR agonism with butyrylcholinesterase inhibition, a synergistic neuroprotective action against Alzheimer's disease.

Journal: RSC medicinal chemistry

Published: March 30, 2026

An efficient step-by-step approach to select pleiotropic drug candidates against Alzheimer's disease: The discovery of neocopride.

An efficient step-by-step approach to select pleiotropic drug candidates against Alzheimer's disease: The discovery of neocopride.

Journal: Journal of Alzheimer's disease : JAD

Published: March 13, 2026

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid-β Production and Cognitive Dysfunctions in Alzheimer's Disease.

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid-β Production and Cognitive Dysfunctions in Alzheimer's Disease.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: November 21, 2025

Phospho-Tau Signature During Mitosis: AT8, p-T217 and p-S422 as Key Phospho-Epitopes.

Phospho-Tau Signature During Mitosis: AT8, p-T217 and p-S422 as Key Phospho-Epitopes.

Journal: Cells

Published: August 03, 2025

The same but different: impact of animal facility sanitary status on a transgenic mouse model of Alzheimer's disease.

The same but different: impact of animal facility sanitary status on a transgenic mouse model of Alzheimer's disease.

Journal: mBio

Published: April 17, 2025

A Sensitive and Versatile Cell-Based Assay Combines Luminescence and Trapping Approaches to Monitor Unconventional Protein Secretion.

A Sensitive and Versatile Cell-Based Assay Combines Luminescence and Trapping Approaches to Monitor Unconventional Protein Secretion.

Journal: Traffic (Copenhagen, Denmark)

Published: December 06, 2024

Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT4 receptors with potential interest in the treatment of Alzheimer's disease.

Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT4 receptors with potential interest in the treatment of Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: September 20, 2024

Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models.

Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models.

Journal: British journal of pharmacology

Published: August 27, 2024

Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer's disease by administration through an intranasal route.

Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer's disease by administration through an intranasal route.

Journal: Communications biology

Published: January 03, 2024

Development of Pleiotropic TrkB and 5-HT4 Receptor Ligands as Neuroprotective Agents.

Development of Pleiotropic TrkB and 5-HT4 Receptor Ligands as Neuroprotective Agents.

Journal: Molecules (Basel, Switzerland)

Published: December 14, 2023

Novel and atypical pathways for serotonin signaling.

Novel and atypical pathways for serotonin signaling.

Journal: Faculty reviews

Published: July 01, 2021

Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease.

Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: August 24, 2020

Showing 1-12 of 34

Last Updated: 09/26/2026