Taha S. Ali

Al Minya, MN, Egypt

Last Updated: 09/26/2026

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Found 46 publications

Neuroprotective effects of an oxindole-piperine hybrid in a rat model of ischemic stroke.

Neuroprotective effects of an oxindole-piperine hybrid in a rat model of ischemic stroke.

Journal: Neuroreport

Published: June 04, 2026

Development of a novel series of thiazole-based compounds with enhanced antiproliferative properties as tubulin polymerization inhibitors.

Development of a novel series of thiazole-based compounds with enhanced antiproliferative properties as tubulin polymerization inhibitors.

Journal: Frontiers in chemistry

Published: February 20, 2026

Discovery of Novel 5-Substituted-4-Allyl-1,2,4-Triazoles as Potential Nonsteroidal Anti-Inflammatory Agents via Downregulation of iNOS Expression.

Discovery of Novel 5-Substituted-4-Allyl-1,2,4-Triazoles as Potential Nonsteroidal Anti-Inflammatory Agents via Downregulation of iNOS Expression.

Journal: Drug development research

Published: February 15, 2026

Design, synthesis, and antiproliferative activity of novel thiazole-based derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.

Design, synthesis, and antiproliferative activity of novel thiazole-based derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.

Journal: RSC advances

Published: February 15, 2026

Integrating synthesis, pharmacological evaluation, and molecular dynamics simulation of novel 8-substituted theophylline hybrids as potential PDE-4B inhibitors, bronchodilators and antibacterial.

Integrating synthesis, pharmacological evaluation, and molecular dynamics simulation of novel 8-substituted theophylline hybrids as potential PDE-4B inhibitors, bronchodilators and antibacterial.

Journal: Bioorganic chemistry

Published: November 10, 2025

Biologically Active Benzimidazole Hybrids as Cancer Therapeutics: Recent Advances.

Biologically Active Benzimidazole Hybrids as Cancer Therapeutics: Recent Advances.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: August 13, 2025

Antimicrobial activity and antifungal mechanistic study of 3‑substituted oxindoles against Aspergillus niger.

Antimicrobial activity and antifungal mechanistic study of 3‑substituted oxindoles against Aspergillus niger.

Journal: Scientific reports

Published: July 10, 2025

Design, Synthesis, and In Vitro Anticancer Evaluation of Thiazole-Based Chalcones Linked to Sulfanilamide as Tumor-Associated Carbonic Anhydrase IX and XII Inhibitors.

Design, Synthesis, and In Vitro Anticancer Evaluation of Thiazole-Based Chalcones Linked to Sulfanilamide as Tumor-Associated Carbonic Anhydrase IX and XII Inhibitors.

Journal: Journal of medicinal chemistry

Published: July 07, 2025

Targeting melanoma resistance: Novel oxindole and non-oxindole-based benzimidazole derivatives as potent dual inhibitors of BRAFV600E and ABL2 kinases.

Targeting melanoma resistance: Novel oxindole and non-oxindole-based benzimidazole derivatives as potent dual inhibitors of BRAFV600E and ABL2 kinases.

Journal: European journal of medicinal chemistry

Published: June 17, 2025

Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors.

Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors.

Journal: Frontiers in chemistry

Published: January 23, 2025

The protective role of two oxindole derivatives is mediated by modulating NLRP3/caspase-1 and PI3K/AKT pathways in a preclinical animal model of hepatic ischemia reperfusion injury.

The protective role of two oxindole derivatives is mediated by modulating NLRP3/caspase-1 and PI3K/AKT pathways in a preclinical animal model of hepatic ischemia reperfusion injury.

Journal: Life sciences

Published: April 25, 2024

Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor.

Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: April 23, 2024

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Last Updated: 09/26/2026