Takaaki Sumiyoshi

Suita, 5648680, Japan

Last Updated: 09/26/2026

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Found 23 publications

Improving ADME Prediction with Multitask Graph Neural Networks and Assessing Explainability in Lead Optimization.

Improving ADME Prediction with Multitask Graph Neural Networks and Assessing Explainability in Lead Optimization.

Journal: Journal of chemical information and modeling
Published: October 22, 2025

Experimental and DFT Studies of Intermolecular Interaction-Assisted Oxindole Cyclization Reaction of Di-t-butyl 2-Aminophenyl-2-methyl Malonate.

Experimental and DFT Studies of Intermolecular Interaction-Assisted Oxindole Cyclization Reaction of Di-t-butyl 2-Aminophenyl-2-methyl Malonate.

Journal: Chemical & pharmaceutical bulletin
Published: January 29, 2025

Asymmetric Synthesis, Structure Determination, and Biologic Evaluation of Isomers of TLAM as PFK1 Inhibitors.

Asymmetric Synthesis, Structure Determination, and Biologic Evaluation of Isomers of TLAM as PFK1 Inhibitors.

Journal: ACS medicinal chemistry letters
Published: September 02, 2024

Acquired curved hair is caused by fusion of multiple hair matrix cells.

Acquired curved hair is caused by fusion of multiple hair matrix cells.

Journal: Journal of dermatological science
Published: July 21, 2023

Cloning of two gene clusters involved in the catabolism of 2,4-dinitrophenol by Paraburkholderia sp. strain KU-46 and characterization of the initial DnpAB enzymes and a two-component monooxygenases DnpC1C2.

Cloning of two gene clusters involved in the catabolism of 2,4-dinitrophenol by Paraburkholderia sp. strain KU-46 and characterization of the initial DnpAB enzymes and a two-component monooxygenases DnpC1C2.

Journal: Journal of bioscience and bioengineering
Published: March 14, 2023

Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors.

Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors.

Journal: ACS medicinal chemistry letters
Published: July 21, 2022

Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood-Brain Barrier.

Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood-Brain Barrier.

Journal: Pharmaceutics
Published: June 21, 2022

MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke.

MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke.

Journal: Scientific reports
Published: April 12, 2022

GPR91 antagonist and TGF-β inhibitor suppressed collagen production of high glucose and succinate induced HSC activation.

GPR91 antagonist and TGF-β inhibitor suppressed collagen production of high glucose and succinate induced HSC activation.

Journal: Biochemical and biophysical research communications
Published: July 27, 2020

A novel piperidine degradation mechanism in a newly isolated piperidine degrader Pseudomonas sp. strain KU43P.

A novel piperidine degradation mechanism in a newly isolated piperidine degrader Pseudomonas sp. strain KU43P.

Journal: The Journal of general and applied microbiology
Published: July 10, 2020

Design, synthesis and evaluations of spiro-fused benzoxaborin derivatives as novel boron-containing compounds.

Design, synthesis and evaluations of spiro-fused benzoxaborin derivatives as novel boron-containing compounds.

Journal: Chemical biology & drug design
Published: November 09, 2018

Design, Synthesis, and Blood-Brain Barrier Transport Study of Pyrilamine Derivatives as Histone Deacetylase Inhibitors.

Design, Synthesis, and Blood-Brain Barrier Transport Study of Pyrilamine Derivatives as Histone Deacetylase Inhibitors.

Journal: ACS medicinal chemistry letters
Published: February 28, 2018
Showing 1-12 of 23

Last Updated: 09/26/2026