Takaaki Yokota
Chuo, Japan
Last Updated: 09/26/2026
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Found 11 publications
Effect of add-on naldemedine treatment in patients with cancer and opioid-induced constipation insufficiently responding to magnesium oxide: a pooled, subgroup analysis of two randomized controlled trials.
Journal: Japanese journal of clinical oncology
Published: July 03, 2024
Efficacy of Naldemedine on Intestinal Hypomotility and Adhesions in Rodent Models of Postoperative Ileus.
Journal: Biological & pharmaceutical bulletin
Published: October 19, 2023
Naldemedine is effective in the treatment of opioid-induced constipation in patients with chronic non-cancer pain who had a poor response to laxatives.
Journal: Therapeutic advances in gastroenterology
Published: May 20, 2020
Naldemedine: Peripherally Acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects.
Journal: Current topics in medicinal chemistry
Published: January 30, 2020
Safety and efficacy of naldemedine in cancer patients with opioid-induced constipation: a pooled, subgroup analysis of two randomised controlled studies.
Journal: ESMO open
Published: April 11, 2019
The Influence of Renal or Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Naldemedine.
Journal: Clinical pharmacology in drug development
Published: February 04, 2019
Naldemedine in Japanese patients with opioid-induced constipation and chronic noncancer pain: open-label Phase III studies.
Journal: Journal of pain research
Published: January 08, 2019
Reply to Y. Yagi et al.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: February 07, 2018
Randomized Phase III and Extension Studies of Naldemedine in Patients With Opioid-Induced Constipation and Cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: October 03, 2017
Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients With Cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: April 27, 2017
Phase 1, Randomized, Double-Blind, Placebo-Controlled Studies on the Safety, Tolerability, and Pharmacokinetics of Naldemedine in Healthy Volunteers.
Journal: Clinical pharmacology in drug development
Published: April 12, 2017
Showing 1-11 of 11
Last Updated: 09/26/2026