Takahiro Seki

Toyonaka, 5610825, Japan

Last Updated: 09/26/2026

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Found 15 publications

Molecular design and evaluation of aza-polycyclic carbamoyl pyridones as HIV-1 integrase strand transfer inhibitors.

Molecular design and evaluation of aza-polycyclic carbamoyl pyridones as HIV-1 integrase strand transfer inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: April 25, 2024

New designs for HIV-1 integrase inhibitors: a patent review (2018-present).

New designs for HIV-1 integrase inhibitors: a patent review (2018-present).

Journal: Expert opinion on therapeutic patents

Published: February 08, 2023

Discovery of tricyclic HIV-1 integrase-LEDGF/p75 allosteric inhibitors by intramolecular direct arylation reaction.

Discovery of tricyclic HIV-1 integrase-LEDGF/p75 allosteric inhibitors by intramolecular direct arylation reaction.

Journal: Bioorganic & medicinal chemistry letters

Published: December 26, 2021

Discovery of novel HIV-1 integrase-LEDGF/p75 allosteric inhibitors based on a pyridine scaffold forming an intramolecular hydrogen bond.

Discovery of novel HIV-1 integrase-LEDGF/p75 allosteric inhibitors based on a pyridine scaffold forming an intramolecular hydrogen bond.

Journal: Bioorganic & medicinal chemistry letters

Published: October 09, 2020

Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.

Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.

Journal: Bioorganic & medicinal chemistry

Published: June 03, 2020

Construction of a Nonnatural C60 Carotenoid Biosynthetic Pathway.

Construction of a Nonnatural C60 Carotenoid Biosynthetic Pathway.

Journal: ACS synthetic biology

Published: January 29, 2019

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life.

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life.

Journal: Journal of molecular biology

Published: November 07, 2018

Barrier to Resistance of Dolutegravir in Two-Drug Combinations.

Barrier to Resistance of Dolutegravir in Two-Drug Combinations.

Journal: Antimicrobial agents and chemotherapy

Published: October 03, 2018

Novel secondary mutations C56S and G149A confer resistance to HIV-1 integrase strand transfer inhibitors.

Novel secondary mutations C56S and G149A confer resistance to HIV-1 integrase strand transfer inhibitors.

Journal: Antiviral research

Published: October 16, 2017

Effects of raltegravir or elvitegravir resistance signature mutations on the barrier to dolutegravir resistance in vitro.

Effects of raltegravir or elvitegravir resistance signature mutations on the barrier to dolutegravir resistance in vitro.

Journal: Antimicrobial agents and chemotherapy

Published: November 19, 2014

Antiviral characteristics of GSK1265744, an HIV integrase inhibitor dosed orally or by long-acting injection.

Antiviral characteristics of GSK1265744, an HIV integrase inhibitor dosed orally or by long-acting injection.

Journal: Antimicrobial agents and chemotherapy

Published: November 05, 2014

The relationship between in vivo antiviral activity and pharmacokinetic parameters of peramivir in influenza virus infection model in mice.

The relationship between in vivo antiviral activity and pharmacokinetic parameters of peramivir in influenza virus infection model in mice.

Journal: Antiviral research

Published: February 11, 2014

Showing 1-12 of 15

Last Updated: 09/26/2026