Takao Sanaki

Osaka, Japan

Last Updated: 09/26/2026

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Found 25 publications

Synergistic antiviral activity of a cathepsin B/L inhibitor and a TMPRSS2 inhibitor against SARS-CoV-2 in vitro and in vivo.

Synergistic antiviral activity of a cathepsin B/L inhibitor and a TMPRSS2 inhibitor against SARS-CoV-2 in vitro and in vivo.

Journal: Virology

Published: May 22, 2025

Ensitrelvir as a novel treatment option for mild-to-moderate COVID-19: a narrative literature review.

Ensitrelvir as a novel treatment option for mild-to-moderate COVID-19: a narrative literature review.

Journal: Therapeutic advances in infectious disease

Published: October 17, 2024

Prevention of post COVID-19 condition by early treatment with ensitrelvir in the phase 3 SCORPIO-SR trial.

Prevention of post COVID-19 condition by early treatment with ensitrelvir in the phase 3 SCORPIO-SR trial.

Journal: Antiviral research

Published: April 02, 2024

Efficacy and Safety of 5-Day Oral Ensitrelvir for Patients With Mild to Moderate COVID-19: The SCORPIO-SR Randomized Clinical Trial.

Efficacy and Safety of 5-Day Oral Ensitrelvir for Patients With Mild to Moderate COVID-19: The SCORPIO-SR Randomized Clinical Trial.

Journal: JAMA network open

Published: February 09, 2024

Efficacy and Safety of Ensitrelvir for Asymptomatic or Mild COVID-19: An Exploratory Analysis of a Multicenter, Randomized, Phase 2b/3 Clinical Trial.

Efficacy and Safety of Ensitrelvir for Asymptomatic or Mild COVID-19: An Exploratory Analysis of a Multicenter, Randomized, Phase 2b/3 Clinical Trial.

Journal: Influenza and other respiratory viruses

Published: October 12, 2023

A phase 2/3 study of S-217622 in participants with SARS-CoV-2 infection (Phase 3 part).

A phase 2/3 study of S-217622 in participants with SARS-CoV-2 infection (Phase 3 part).

Journal: Medicine

Published: February 24, 2023

S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.

S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.

Journal: Science translational medicine

Published: November 03, 2022

A Randomized Phase 2/3 Study of Ensitrelvir, a Novel Oral SARS-CoV-2 3C-Like Protease Inhibitor, in Japanese Patients with Mild-to-Moderate COVID-19 or Asymptomatic SARS-CoV-2 Infection: Results of the Phase 2a Part.

A Randomized Phase 2/3 Study of Ensitrelvir, a Novel Oral SARS-CoV-2 3C-Like Protease Inhibitor, in Japanese Patients with Mild-to-Moderate COVID-19 or Asymptomatic SARS-CoV-2 Infection: Results of the Phase 2a Part.

Journal: Antimicrobial agents and chemotherapy

Published: September 13, 2022

Efficacy and Safety of Ensitrelvir in Patients With Mild-to-Moderate Coronavirus Disease 2019: The Phase 2b Part of a Randomized, Placebo-Controlled, Phase 2/3 Study.

Efficacy and Safety of Ensitrelvir in Patients With Mild-to-Moderate Coronavirus Disease 2019: The Phase 2b Part of a Randomized, Placebo-Controlled, Phase 2/3 Study.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Published: August 11, 2022

Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19.

Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19.

Journal: Journal of medicinal chemistry

Published: March 30, 2022

Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model.

Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model.

Journal: The Journal of antimicrobial chemotherapy

Published: March 28, 2022

Characterization of the In Vitro and In Vivo Efficacy of Baloxavir Marboxil against H5 Highly Pathogenic Avian Influenza Virus Infection.

Characterization of the In Vitro and In Vivo Efficacy of Baloxavir Marboxil against H5 Highly Pathogenic Avian Influenza Virus Infection.

Journal: Viruses

Published: December 28, 2021

Showing 1-12 of 25

Last Updated: 09/26/2026