Takeshi Yokoyama

Sugitani, 9300914, Japan

Last Updated: 09/26/2026

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Found 43 publications

Identification of Acoramidis as a Repurposed Inhibitor of the DNA Sanitization Enzyme MutT Homologue 1.

Identification of Acoramidis as a Repurposed Inhibitor of the DNA Sanitization Enzyme MutT Homologue 1.

Journal: ACS pharmacology & translational science

Published: December 03, 2025

Glycosidic scaffold bearing multiple galloyl moieties from pomegranate disrupts transthyretin amyloids.

Glycosidic scaffold bearing multiple galloyl moieties from pomegranate disrupts transthyretin amyloids.

Journal: iScience

Published: June 02, 2025

Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors.

Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors.

Journal: Journal of medicinal chemistry

Published: January 06, 2025

Divergent Total Synthesis of Isoflavone Natural Products and Their Potential as Therapeutic Agents for TTR Amyloidosis.

Divergent Total Synthesis of Isoflavone Natural Products and Their Potential as Therapeutic Agents for TTR Amyloidosis.

Journal: Journal of natural products

Published: October 27, 2024

Discovery and optimization of isoliquiritigenin as a death-associated protein kinase 1 inhibitor.

Discovery and optimization of isoliquiritigenin as a death-associated protein kinase 1 inhibitor.

Journal: European journal of medicinal chemistry

Published: August 07, 2024

SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD+-binding pocket.

SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD+-binding pocket.

Journal: FEBS letters

Published: May 06, 2024

Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.

Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.

Journal: Journal of medicinal chemistry

Published: April 26, 2024

Structural insights into rapamycin-induced oligomerization of a FRB-FKBP fusion protein.

Structural insights into rapamycin-induced oligomerization of a FRB-FKBP fusion protein.

Journal: FEBS letters

Published: March 07, 2024

Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.

Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.

Journal: Journal of medicinal chemistry

Published: November 01, 2023

Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.

Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.

Journal: Bioorganic & medicinal chemistry

Published: April 24, 2023

Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin.

Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin.

Journal: The FEBS journal

Published: March 19, 2023

Characterization of the molecular interactions between resveratrol derivatives and death-associated protein kinase 1.

Characterization of the molecular interactions between resveratrol derivatives and death-associated protein kinase 1.

Journal: The FEBS journal

Published: March 03, 2023

Showing 1-12 of 43

Last Updated: 09/26/2026