Takuma Irie

Tokyo, 1040045, Japan

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 21 publications

KRAS mutations disrupt interactions between CD8+ T cells and antigen-presenting cells in the tumor microenvironment of biliary tract cancer.

KRAS mutations disrupt interactions between CD8+ T cells and antigen-presenting cells in the tumor microenvironment of biliary tract cancer.

Journal: International immunology

Published: August 18, 2025

Lenvatinib Combined with PD-1 Blockade Therapy Benefits Gastric Cancers through Immunosuppressive Macrophage Modulation.

Lenvatinib Combined with PD-1 Blockade Therapy Benefits Gastric Cancers through Immunosuppressive Macrophage Modulation.

Journal: Cancer immunology research

Published: August 07, 2025

A phase Ib study of photoimmunotherapy with ASP-1929 in combination with nivolumab for advanced gastric cancer (GE-PIT, EPOC1901).

A phase Ib study of photoimmunotherapy with ASP-1929 in combination with nivolumab for advanced gastric cancer (GE-PIT, EPOC1901).

Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Published: March 12, 2025

Coactivation of innate immune suppressive cells induces acquired resistance against combined TLR agonism and PD-1 blockade.

Coactivation of innate immune suppressive cells induces acquired resistance against combined TLR agonism and PD-1 blockade.

Journal: Science translational medicine

Published: February 12, 2025

Atezolizumab following definitive chemoradiotherapy in patients with unresectable locally advanced esophageal squamous cell carcinoma - a multicenter phase 2 trial (EPOC1802).

Atezolizumab following definitive chemoradiotherapy in patients with unresectable locally advanced esophageal squamous cell carcinoma - a multicenter phase 2 trial (EPOC1802).

Journal: Nature cancer

Published: March 15, 2024

Microbiota-driven antitumour immunity mediated by dendritic cell migration.

Microbiota-driven antitumour immunity mediated by dendritic cell migration.

Journal: Nature

Published: January 16, 2023

BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors.

BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors.

Journal: Science immunology

Published: October 07, 2022

Regulatory T-cell development in the tumor microenvironment.

Regulatory T-cell development in the tumor microenvironment.

Journal: European journal of immunology

Published: January 18, 2022

Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer.

Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer.

Journal: JCI insight

Published: December 29, 2021

Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.

Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.

Journal: Science immunology

Published: November 12, 2021

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments.

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments.

Journal: Cancer cell

Published: August 01, 2021

PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes.

PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes.

Journal: Cell reports

Published: February 07, 2021

Showing 1-12 of 21

Last Updated: 09/26/2026