Takuomi Hosaka
Shizuoka, 4228526, Japan
Last Updated: 09/26/2026
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Found 32 publications
Evaluation of the Ligand-Dependent Coactivator Recruitment of the Nuclear Receptor Pregnane X Receptor Using Its Three-Alanine Residues-Inserted Mutant.
Journal: Biological & pharmaceutical bulletin
Published: June 21, 2026
Characterization of the toxicological findings from 90-day and 2-year repeated-dose toxicity studies of pesticides in rats.
Journal: The Journal of toxicological sciences
Published: October 01, 2025
Machine Learning on Toxicogenomic Data Reveals a Strong Association Between the Induction of Drug-Metabolizing Enzymes and Centrilobular Hepatocyte Hypertrophy in Rats.
Journal: International journal of molecular sciences
Published: March 12, 2025
Utility of in vitro assay data in read-across prediction of nongenotoxic carcinogenicity of pesticides for cytotoxicity-related rat tumors.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Published: February 22, 2025
Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates.
Journal: Toxicology in vitro : an international journal published in association with BIBRA
Published: November 18, 2024
Utility of human cytochrome P450 inhibition data in the assessment of drug-induced liver injury.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: February 05, 2024
Interaction with YAP underlies the species differences between humans and rodents in CAR-dependent hepatocyte proliferation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology
Published: December 21, 2023
Involvement of the CYP1A1 inhibition-mediated activation of aryl hydrocarbon receptor in drug-induced hepatotoxicity.
Journal: The Journal of toxicological sciences
Published: September 01, 2022
Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance.
Journal: International journal of molecular sciences
Published: August 01, 2022
Development of a strategy to identify and evaluate direct and indirect activators of constitutive androstane receptor in rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Published: February 26, 2022
Last Updated: 09/26/2026