Tamer M. Ibrahim

Giza, GZ, Egypt

Last Updated: 09/26/2026

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Found 57 publications

Ring-opening simplification of thiazolyl-pyrazoline-triazole hybrids: synthesis, SAR and antifolate mechanism against Leishmania major.

Ring-opening simplification of thiazolyl-pyrazoline-triazole hybrids: synthesis, SAR and antifolate mechanism against Leishmania major.

Journal: RSC medicinal chemistry

Published: May 13, 2026

Identification of novel pyrazolines and isoxazolines as antileishmanial agents via a potential antifolate mechanism: synthesis, biological evaluation, and in silico studies.

Identification of novel pyrazolines and isoxazolines as antileishmanial agents via a potential antifolate mechanism: synthesis, biological evaluation, and in silico studies.

Journal: Bioorganic chemistry

Published: April 23, 2026

Benchmarking docking and ML re-scoring screening performance for KRAS G12D in pancreatic cancer.

Benchmarking docking and ML re-scoring screening performance for KRAS G12D in pancreatic cancer.

Journal: Molecular diversity

Published: January 29, 2026

Thiazole-Semicarbazone Hybrids as Dual-Stage Inhibitors of Leishmania major Growth: Design, Synthesis, and Mechanistic Insights.

Thiazole-Semicarbazone Hybrids as Dual-Stage Inhibitors of Leishmania major Growth: Design, Synthesis, and Mechanistic Insights.

Journal: Drug development research

Published: January 12, 2026

Hepatoprotective Effects of Fused Pyridine Derivatives: Regulation of the TGF-β/Smad, miR-21/Smad7, and PPARγ Pathways in Carbon Tetrachloride-Induced Liver Fibrosis.

Hepatoprotective Effects of Fused Pyridine Derivatives: Regulation of the TGF-β/Smad, miR-21/Smad7, and PPARγ Pathways in Carbon Tetrachloride-Induced Liver Fibrosis.

Journal: Drug design, development and therapy

Published: December 31, 2025

Standards for Computational Methods in Drug Design and Discovery: Simplified Guidance for Authors and Reviewers.

Standards for Computational Methods in Drug Design and Discovery: Simplified Guidance for Authors and Reviewers.

Journal: Drug design, development and therapy

Published: October 10, 2025

Synthesis and Biological Evaluation of Imidazopyridine-Isatin Hybrids as Inhibitors of Leishmania major Growth.

Synthesis and Biological Evaluation of Imidazopyridine-Isatin Hybrids as Inhibitors of Leishmania major Growth.

Journal: Drug design, development and therapy

Published: September 27, 2025

A benchmarking-informed structure-based virtual screening strategy targeting Lm-PTR1: Leveraging the Northern African natural products database.

A benchmarking-informed structure-based virtual screening strategy targeting Lm-PTR1: Leveraging the Northern African natural products database.

Journal: Journal of molecular graphics & modelling

Published: September 25, 2025

An exploration of potent antileishmanial agents derived from quinoline-thiazole and thiadiazole hybrids, targeting DHFR-TS and PTR1: design, synthesis, and computational analyses.

An exploration of potent antileishmanial agents derived from quinoline-thiazole and thiadiazole hybrids, targeting DHFR-TS and PTR1: design, synthesis, and computational analyses.

Journal: RSC medicinal chemistry

Published: August 13, 2025

Piperidine-based small molecules as dual-stage antileishmanial agents targeting parasite folate pathway.

Piperidine-based small molecules as dual-stage antileishmanial agents targeting parasite folate pathway.

Journal: Bioorganic chemistry

Published: July 28, 2025

Design, synthesis and biological evaluation of triazolo[1,5-a]pyrimidine derivatives as new antiproliferative agents with multikinase inhibitory activity.

Design, synthesis and biological evaluation of triazolo[1,5-a]pyrimidine derivatives as new antiproliferative agents with multikinase inhibitory activity.

Journal: Bioorganic chemistry

Published: June 07, 2025

Benchmarking the Structure-Based Virtual Screening Performance of Wild-Type and Resistant PfDHFR Using Docking and Machine Learning Re-Scoring.

Benchmarking the Structure-Based Virtual Screening Performance of Wild-Type and Resistant PfDHFR Using Docking and Machine Learning Re-Scoring.

Journal: Drug design, development and therapy

Published: April 27, 2025

Showing 1-12 of 57

Last Updated: 09/26/2026