Tania Massignan

Trento, 38123, Italy

Last Updated: 09/26/2026

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Found 12 publications

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.

Journal: Science advances

Published: November 24, 2021

Pharmacological inactivation of the prion protein by targeting a folding intermediate.

Pharmacological inactivation of the prion protein by targeting a folding intermediate.

Journal: Communications biology

Published: August 07, 2020

Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface.

Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface.

Journal: Journal of neurochemistry

Published: April 18, 2019

IL-7-induced phosphorylation of the adaptor Crk-like and other targets.

IL-7-induced phosphorylation of the adaptor Crk-like and other targets.

Journal: Cellular signalling

Published: March 16, 2018

A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity.

A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity.

Journal: ChemMedChem

Published: May 18, 2017

An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.

An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.

Journal: PloS one

Published: May 09, 2017

A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.

A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.

Journal: Scientific reports

Published: October 12, 2015

Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.

Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.

Journal: Brain : a journal of neurology

Published: February 14, 2015

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity.

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: February 09, 2013

The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).

The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: June 30, 2012

Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E.

Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E.

Journal: Acta diabetologica

Published: January 14, 2012

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

Journal: PloS one

Published: December 01, 2011

Showing 1-12 of 12

Last Updated: 09/26/2026