Tatjana Barthel

Albert Einstein Str. 15
Berlin, BE 12489, Germany

Last Updated: 09/26/2026

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Found 12 publications

Structure-guided identification and characterization of a novel pyrazolo[1,5-a]pyrimidine ligand of SARS-CoV-2 main protease.

Structure-guided identification and characterization of a novel pyrazolo[1,5-a]pyrimidine ligand of SARS-CoV-2 main protease.

Journal: International journal of biological macromolecules

Published: March 03, 2026

Enhancing the Outcome of Crystallographic Fragment Screening by Choosing the Optimal Protein Crystal Form.

Enhancing the Outcome of Crystallographic Fragment Screening by Choosing the Optimal Protein Crystal Form.

Journal: Small science

Published: August 29, 2025

The macromolecular crystallography beamlines of the Helmholtz-Zentrum Berlin at the BESSY II storage ring: history, current status and future directions.

The macromolecular crystallography beamlines of the Helmholtz-Zentrum Berlin at the BESSY II storage ring: history, current status and future directions.

Journal: Journal of synchrotron radiation

Published: December 17, 2024

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Journal: ACS chemical biology

Published: January 17, 2024

Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.

Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.

Journal: Journal of medicinal chemistry

Published: October 19, 2022

DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis.

DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis.

Journal: Nature catalysis

Published: October 29, 2021

Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.

Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 22, 2021

Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking.

Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking.

Journal: Acta crystallographica. Section D, Structural biology

Published: June 03, 2021

Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin.

Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin.

Journal: Journal of visualized experiments : JoVE

Published: March 22, 2021

Facilitated crystal handling using a simple device for evaporation reduction in microtiter plates.

Facilitated crystal handling using a simple device for evaporation reduction in microtiter plates.

Journal: Journal of applied crystallography

Published: October 22, 2020

FragMAXapp: crystallographic fragment-screening data-analysis and project-management system.

FragMAXapp: crystallographic fragment-screening data-analysis and project-management system.

Journal: Acta crystallographica. Section D, Structural biology

Published: September 25, 2020

F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.

F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.

Journal: Structure (London, England : 1993)

Published: February 14, 2020

Showing 1-12 of 12

Last Updated: 09/26/2026