Terri L. Petkau
Vancouver, BC V6H0B3, Canada
Last Updated: 09/26/2026
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Found 21 publications
Humanized mice carrying a pathogenic GRN deletion as a pre-clinical platform for targeted gene therapies in frontotemporal dementia.
Journal: Neurobiology of disease
Published: March 06, 2026
Design and development of lipid nanoparticle formulations for brain gene therapy.
Journal: Molecular therapy. Nucleic acids
Published: August 19, 2025
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.
Journal: The Journal of biological chemistry
Published: September 18, 2023
FTD-associated behavioural and transcriptomic abnormalities in 'humanized' progranulin-deficient mice: A novel model for progranulin-associated FTD.
Journal: Neurobiology of disease
Published: March 15, 2023
AAV5-miHTT-mediated huntingtin lowering improves brain health in a Huntington's disease mouse model.
AAV5-miHTT-mediated huntingtin lowering improves brain health in a Huntington's disease mouse model.
Journal: Brain : a journal of neurology
Published: January 28, 2022
Intracerebroventricular Administration of AAV9-PHP.B SYN1-EmGFP Induces Widespread Transgene Expression in the Mouse and Monkey Central Nervous System.
Journal: Human gene therapy
Published: April 16, 2021
Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles.
Journal: Nanoscale
Published: November 26, 2020
Human progranulin-expressing mice as a novel tool for the development of progranulin-modulating therapeutics.
Journal: Neurobiology of disease
Published: July 02, 2020
A novel mouse model for pyridoxine-dependent epilepsy due to antiquitin deficiency.
Journal: Human molecular genetics
Published: April 23, 2020
Isolating cells from adult murine brain for validation of cell-type specific cre-mediated deletion.
Journal: Journal of neuroscience methods
Published: February 13, 2019
Mutant huntingtin expression in microglia is neither required nor sufficient to cause the Huntington's disease-like phenotype in BACHD mice.
Journal: Human molecular genetics
Published: October 26, 2018
Last Updated: 09/26/2026